CD133-B19, 5'-DY647

Pricing Availability Delivery Time Qty
Cat.No. 6104 - CD133-B19, 5'-DY647 | C221H263F10N73O131P20
Description: High affinity fluorescently tagged aptamer for CD133 (extracellular domain epitope)

Biological Activity

High affinity fluorescently tagged aptamer for CD133 (extracellular domaine epitope) (Kd values are 52.3 and 145.1 nM in Hep3B and HT29 cells, respectively). Efficiently internalized upon binding to CD133. Exhibits superior penetration of tumorspheres compared with an antibody to the same target.

For optimal binding aptamers require refolding into their tertiary structure prior to use. Please refer to the accompanying protocol for information regarding refolding and aptamer use in unfixed cell imaging and flow cytometry.

Licensing Information

Sold under license from the patent holder, Deakin University.

Technical Data

M. Wt 6847.32
Formula C221H263F10N73O131P20
Storage Store at -20°C
Aptamer type (DNA/RNA) RNA
Number of Bases 19
Sequence Modifications 2-fluoropyrimidines, 3'-inverted deoxythymidine cap, 5'-fluorescent DY647 tag

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.


Please refer to these solubility guidelines for CD133-B19, 5'-DY647 (Cat.No. 6104).

Preparing Stock Solutions

The following data is based on the product molecular weight 6847.32. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 0.15 mL 0.73 mL 1.46 mL
5 mM 0.03 mL 0.15 mL 0.29 mL
10 mM 0.01 mL 0.07 mL 0.15 mL
50 mM 0 mL 0.01 mL 0.03 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.


Dilution Calculator

Calculate the dilution required to prepare a stock solution.

Product Datasheets

Safety Datasheet


References are publications that support the products' biological activity.

Shigdar et al (2013) RNA aptamers targeting cancer stem cell marker CD133. Cancer Lett. 330 84 PMID: 23196060

If you know of a relevant reference for CD133-B19, 5'-DY647, please let us know.

Keywords: CD133-B19, 5'-DY647, supplier, CD133-B19-5-DY647, Aptamers, CD133, extracellular, domain, epitope, fluorescent, high, affinity, Prominin-1, Fluorescent, Probes, Cancer, Stem, Cells, Aptamers, Aptamers, Tocris Bioscience

Citations for CD133-B19, 5'-DY647

Citations are publications that use Tocris products.

Currently there are no citations for CD133-B19, 5'-DY647. Do you know of a great paper that uses CD133-B19, 5'-DY647 from Tocris? If so please let us know.

Reviews for CD133-B19, 5'-DY647

There are currently no reviews for this product. Be the first to review CD133-B19, 5'-DY647 and earn rewards!

Have you used CD133-B19, 5'-DY647?

Submit a review and receive an Amazon gift card.

$10US/$10CAN/€7/£6 gift card for a review without an image

$25US/$25CAN/€18/£15 gift card for a review with an image

*Offer only valid in the USA / Canada, UK and Europe

Submit a Review

Literature in this Area


Cancer Research Product Guide

A collection of over 750 products for cancer research, the guide includes research tools for the study of:

  • Cancer Metabolism
  • Epigenetics in Cancer
  • Receptor Signaling
  • Cell Cycle and DNA Damage Repair
  • Angiogenesis
  • Invasion and Metastasis
Stem Cells

Stem Cells Scientific Review

Written by Kirsty E. Clarke, Victoria B. Christie, Andy Whiting and Stefan A. Przyborski, this review provides an overview of the use of small molecules in the control of stem cell growth and differentiation. Key signaling pathways are highlighted, and the regulation of ES cell self-renewal and somatic cell reprogramming is discussed. Compounds available from Tocris are listed.