CD133-B19, 5'-DY647

Discontinued Product

CD133-B19, 5'-DY647 (Cat. No. 6104) has been withdrawn from sale for commercial reasons.
Description: High affinity fluorescently tagged aptamer for CD133 (extracellular domain epitope)
Literature (1)

Biological Activity for CD133-B19, 5'-DY647

CD133-B19, 5'-DY647 is a high affinity fluorescently tagged aptamer for CD133 (extracellular domaine epitope) (Kd values are 52.3 and 145.1 nM in Hep3B and HT29 cells, respectively). Efficiently internalized upon binding to CD133. Exhibits superior penetration of tumorspheres compared with an antibody to the same target.

For optimal binding aptamers require refolding into their tertiary structure prior to use. Please refer to the protocol for information regarding refolding and aptamer use in unfixed cell imaging and flow cytometry.

Licensing Information

Sold under license from the patent holder, Deakin University.

Technical Data for CD133-B19, 5'-DY647

Aptamer type (DNA/RNA) RNA
Number of Bases 19
Sequence Modifications 2-fluoropyrimidines, 3'-inverted deoxythymidine cap, 5'-fluorescent DY647 tag
M. Wt 6847.32
Formula C221H263F10N73O131P20
Storage Store at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for CD133-B19, 5'-DY647

Please refer to these solubility guidelines for CD133-B19, 5'-DY647 (Cat. No. 6104).

Product Datasheets for CD133-B19, 5'-DY647

References for CD133-B19, 5'-DY647

References are publications that support the biological activity of the product.

Shigdar et al (2013) RNA aptamers targeting cancer stem cell marker CD133. Cancer Lett. 330 84 PMID: 23196060

Keywords: CD133-B19, 5'-DY647, CD133-B19, 5'-DY647 supplier, CD133-B19-5-DY647, Aptamers, CD133, extracellular, domain, epitope, fluorescent, high, affinity, Prominin-1, Cancer, Stem, Cells, Fluorescent, Cell, Surface, Markers, 6104, Tocris Bioscience

Citations for CD133-B19, 5'-DY647

Citations are publications that use Tocris products.

Currently there are no citations for CD133-B19, 5'-DY647.

Reviews for CD133-B19, 5'-DY647

There are currently no reviews for this product. Be the first to review CD133-B19, 5'-DY647 and earn rewards!

Have you used CD133-B19, 5'-DY647?

Submit a review and receive an Amazon gift card.

$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review

Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.

Fluorescent Dyes and Probes Research Product Guide

Fluorescent Dyes and Probes Research Product Guide

This product guide provides a background to the use of Fluorescent Dyes and Probes, as well as a comprehensive list of our:

  • Fluorescent Dyes, including dyes for flow cytometry
  • Fluorescent Probes and Stains, including our new MitoBrilliantTM mitochondria stains
  • Tissue Clearing Kits and Reagents
  • Aptamer-based RNA Imaging Reagents
  • Fluorescent Probes for Imaging Bacteria
  • TSA VividTM Fluorophore Kits
  • TSA Reagents for Enhancing IHC, ICC & FISH Signals