CD133-B19, 5'-DY647

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Cat.No. 6104 - CD133-B19, 5'-DY647 | C221H263F10N73O131P20
Description: High affinity fluorescently tagged aptamer for CD133 (extracellular domain epitope)
Protocols (1)

Biological Activity

High affinity fluorescently tagged aptamer for CD133 (extracellular domaine epitope) (Kd values are 52.3 and 145.1 nM in Hep3B and HT29 cells, respectively). Efficiently internalized upon binding to CD133. Exhibits superior penetration of tumorspheres compared with an antibody to the same target.

For optimal binding aptamers require refolding into their tertiary structure prior to use. Please refer to the protocol for information regarding refolding and aptamer use in unfixed cell imaging and flow cytometry.

Licensing Information

Sold under license from the patent holder, Deakin University.

Technical Data

M. Wt 6847.32
Formula C221H263F10N73O131P20
Storage Store at -20°C
Aptamer type (DNA/RNA) RNA
Number of Bases 19
Sequence Modifications 2-fluoropyrimidines, 3'-inverted deoxythymidine cap, 5'-fluorescent DY647 tag

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.


Please refer to these solubility guidelines for CD133-B19, 5'-DY647 (Cat. No. 6104).


References are publications that support the biological activity of the product.

Shigdar et al (2013) RNA aptamers targeting cancer stem cell marker CD133. Cancer Lett. 330 84 PMID: 23196060

If you know of a relevant reference for CD133-B19, 5'-DY647, please let us know.

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Citations for CD133-B19, 5'-DY647

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Protocols for CD133-B19, 5'-DY647

The following protocol features additional information for the use of CD133-B19, 5'-DY647 (Cat. No. 6104).

Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.


Cancer Research Product Guide

A collection of over 750 products for cancer research, the guide includes research tools for the study of:

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