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Potent, selective, irreversible I2 ligand. Ki values are 1.7, and 1900 nM for I2, and α2-adrenoceptors respectively and the IC50 value at I1 sites is 6400 nM.
|Storage||Desiccate at +4°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
References are publications that support the biological activity of the product.
Coates et al (2000) Probes for imidazoline binding sites: synthesis and evaluation of a selective, irreversible I2 ligand. Bioorg.Med.Chem.Lett. 10 605 PMID: 10741563
Tyacke et al (2000) In vivo activation of imidazoline2 binding sites by a novel irreversible ligand. Br.J.Pharmacol. 131 38P
Keywords: BU 99006, BU 99006 supplier, I2, Receptors, 1320, Tocris Bioscience
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