BU 99006

Discontinued Product

Unfortunately BU 99006 (Cat. No. 1320) has been withdrawn from sale for commercial reasons.
Cat.No. 1320 - BU 99006
Description: Potent, selective, irreversible I2 ligand
Chemical Name: 2-(5-Isothiocyanatobenzofuranyl)imidazoline

Biological Activity

Potent, selective, irreversible I2 ligand. Ki values are 1.7, and 1900 nM for I2, and α2-adrenoceptors respectively and the IC50 value at I1 sites is 6400 nM.

Technical Data

M. Wt 243.28
Storage Desiccate at +4°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Preparing Stock Solutions

The following data is based on the product molecular weight 243.28. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 4.11 mL 20.55 mL 41.1 mL
5 mM 0.82 mL 4.11 mL 8.22 mL
10 mM 0.41 mL 2.06 mL 4.11 mL
50 mM 0.08 mL 0.41 mL 0.82 mL

Molarity Calculator

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*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

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Product Datasheets

Certificate of Analysis is currently unavailable on-line.
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Safety Datasheet is currently unavailable on-line.
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References are publications that support the products' biological activity.

Coates et al (2000) Probes for imidazoline binding sites: synthesis and evaluation of a selective, irreversible I2 ligand. Bioorg.Med.Chem.Lett. 10 605 PMID: 10741563

Tyacke et al (2000) In vivo activation of imidazoline2 binding sites by a novel irreversible ligand. Br.J.Pharmacol. 131 38P PMID:

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Keywords: BU 99006, supplier, I2, Receptors, I2, Receptors, Tocris Bioscience

Citations for BU 99006

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Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!

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New Product Guide

New Product Guide (Spring/Summer 2018)

Our new product guide highlights over 200 new products added to the Tocris Bioscience range during the second half of 2017.

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