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Submit ReviewSelective P2X purinoceptor agonist.
M. Wt | 593.14 |
Storage | Desiccate at -20°C |
CAS Number | 87562-48-9 |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
References are publications that support the biological activity of the product.
Hourani et al (1986) Pharmacological effects of L-AMP-PCP on ATP receptors in smooth muscle. Eur.J.Pharmacol. 131 99 PMID: 3816951
von Kugelgen et al (1992) Stable adenine nucleotides inhibit [3H]-noradrenaline release in rabbit brain cortex slices by direct action at presynaptic adenosine A1-receptors. Naunyn Schmiedebergs Arch.Pharmacol. 346 187 PMID: 1448182
Keywords: b,g-Methylene-L-adenosine 5'-triphosphate tetrasodium, b,g-Methylene-L-adenosine 5'-triphosphate tetrasodium supplier, P2X, Receptors, 1090, Tocris Bioscience
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Peripheral sensitization is the reduction in the threshold of excitability of sensory neurons that results in an augmented response to a given external stimulus. This poster outlines the excitatory and inhibitory signaling pathways involved in modulation of peripheral sensitization. The role of ion channels, GPCRs, neurotrophins, and cytokines in sensory neurons are also described.