β,γ-Methylene-L-adenosine 5'-triphosphate tetrasodium
Discontinued ProductUnfortunately β,γ-Methylene-L-adenosine 5'-triphosphate tetrasodium (Cat. No. 1090) has been withdrawn from sale for commercial reasons.
Selective P2X purinoceptor agonist.
|Storage||Desiccate at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Preparing Stock Solutions
The following data is based on the product molecular weight 593.14. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.69 mL||8.43 mL||16.86 mL|
|5 mM||0.34 mL||1.69 mL||3.37 mL|
|10 mM||0.17 mL||0.84 mL||1.69 mL|
|50 mM||0.03 mL||0.17 mL||0.34 mL|
References are publications that support the products' biological activity.
Hourani et al (1986) Pharmacological effects of L-AMP-PCP on ATP receptors in smooth muscle. Eur.J.Pharmacol. 131 99 PMID: 3816951
von Kugelgen et al (1992) Stable adenine nucleotides inhibit [3H]-noradrenaline release in rabbit brain cortex slices by direct action at presynaptic adenosine A1-receptors. Naunyn Schmiedebergs Arch.Pharmacol. 346 187 PMID: 1448182
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Keywords: b,g-Methylene-L-adenosine 5'-triphosphate tetrasodium, supplier, P2X, Receptors, P2X, Receptors, Tocris Bioscience
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Literature in this Area
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Peripheral sensitization is the reduction in the threshold of excitability of sensory neurons that results in an augmented response to a given external stimulus. This poster outlines the excitatory and inhibitory signaling pathways involved in modulation of peripheral sensitization. The role of ion channels, GPCRs, neurotrophins, and cytokines in sensory neurons are also described.