Anti-human ErbB2 aptamer, Janelia Fluor® 646 conjugate

Discontinued Product

Anti-human ErbB2 aptamer, Janelia Fluor® 646 conjugate (Cat. No. 6557) has been withdrawn from sale for commercial reasons.
Description: High affinity anti-human ErbB2 aptamer conjugated to Janelia Fluor® 646
Datasheet
Citations
Reviews
Literature (1)

Biological Activity

Anti-human ErbB2 aptamer, Janelia Fluor® 646 conjugate is a high affinity anti-human ErbB2 aptamer conjugated to Janelia Fluor® 646 (Kd = 13 nM). Exhibits high affinity and specificity for ErbB2. Displays dense labeling of the stained structures. Suitable for use in super-resolution microscopy techniques.

For optimal binding, aptamers require refolding into their tertiary structure prior to use. Please refer to the protocol for information regarding refolding.

Licensing Information

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus

Technical Data

Aptamer type (DNA/RNA) DNA
Number of Bases 40
Sequence Modifications 3'-inverted deoxythymidine cap, 5'-fluorescent Janelia Fluor® 646 tag
M. Wt 15126.9
Storage Store at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility

Please refer to these solubility guidelines for Anti-human ErbB2 aptamer, Janelia Fluor® 646 conjugate (Cat. No. 6557).

References

References are publications that support the biological activity of the product.

Pala et al (2014) Tumor-specific hyperthermia with aptamer-tagged superparamagnetic nanoparticles. Int.J.Nanomedicine 9 67 PMID: 24379664

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