5-TAMRA SE

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Cat.No. 5441 - 5-TAMRA SE | C29H25N3O7 | CAS No. 150810-68-7
Description: Fluorescent reagent for the labeling of amines
Chemical Name: 5-Carboxytetramethylrhodamine succinimidyl ester
Purity: ≥95% (HPLC)
Datasheet
Citations
Literature

Biological Activity

Fluorescent probe for DNA and RNA; amine-reactive. Also shown to stain telomeres. Nuclease resistant and nuclei permeable. Excitation\emission λ ~545\580 nm.

Technical Data

M. Wt 527.52
Formula C29H25N3O7
Storage Store at -20°C
Purity ≥95% (HPLC)
CAS Number 150810-68-7
PubChem ID 2762600
InChI Key VWFRSNKRTNUMET-UHFFFAOYSA-N
Smiles CN(C)C1=CC=C(C(C2=CC=C(C(ON3C(CCC3=O)=O)=O)C=C2C([O-])=O)=C(C=C/4)C(O5)=CC4=[N+](C)\C)C5=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

SolubilitySoluble in Acetonitrile and in DMF

Preparing Stock Solutions

The following data is based on the product molecular weight 527.52. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.9 mL 9.48 mL 18.96 mL
5 mM 0.38 mL 1.9 mL 3.79 mL
10 mM 0.19 mL 0.95 mL 1.9 mL
50 mM 0.04 mL 0.19 mL 0.38 mL

Molarity Calculator

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Reconstitution Calculator

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Product Datasheets

Safety Datasheet

References

References are publications that support the products' biological activity.

Hirata et al (2014) Structural evaluation of tandem hairpin pyrrole-imidazole polyamides recognizing human telomeres. J.Am.Chem.Soc. 136 11546 PMID: 25036716

Kvach et al (2009) Practical synthesis of isomerically pure 5- and 6-carboxytetramethylrhodamines, useful dyes for DNA probes. Bioconjug. Chem. 20 1673 PMID: 19606815


If you know of a relevant reference for 5-TAMRA SE, please let us know.

Keywords: 5-TAMRASE amine-reactive yellow fluorescent labels Fluorescent Dyes

Citations for 5-TAMRA SE

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New Product Guide

New Product Guide (Spring/Summer 2017)

Our new product guide highlights over 130 new products added to the Tocris Bioscience range during the first half of 2017.

  • 7-TM Receptors
  • Enzymes
  • Enzyme-Linked Receptors
  • Ion Channels
  • Nuclear Receptors
  • Transporters
  • Apoptosis
  • Cell Metabolism
  • Epigenetics
  • Fluorescent Imaging
  • Signal Transduction
  • Stem Cells

Pathways for 5-TAMRA SE

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