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Cat.No. 5441 - 5-TAMRA SE | C29H25N3O7 | CAS No. 150810-68-7
Description: Fluorescent dye for the labeling of amines
Chemical Name: 5-Carboxytetramethylrhodamine succinimidyl ester
Purity: ≥95% (HPLC)

Biological Activity

Fluorescent probe for DNA and RNA; amine-reactive. Also shown to stain telomeres. Nuclease resistant and nuclei permeable. Excitation\emission λ ~545\580 nm.

Technical Data

M. Wt 527.52
Formula C29H25N3O7
Storage Store at -20°C
Purity ≥95% (HPLC)
CAS Number 150810-68-7
PubChem ID 2762600
Smiles CN(C)C1=CC=C(C(C2=CC=C(C(ON3C(CCC3=O)=O)=O)C=C2C([O-])=O)=C(C=C/4)C(O5)=CC4=[N+](C)\C)C5=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

Solubility Soluble in Acetonitrile and in DMF

Preparing Stock Solutions

The following data is based on the product molecular weight 527.52. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.9 mL 9.48 mL 18.96 mL
5 mM 0.38 mL 1.9 mL 3.79 mL
10 mM 0.19 mL 0.95 mL 1.9 mL
50 mM 0.04 mL 0.19 mL 0.38 mL

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Product Datasheets

Safety Datasheet


References are publications that support the biological activity of the product.

Hirata et al (2014) Structural evaluation of tandem hairpin pyrrole-imidazole polyamides recognizing human telomeres. J.Am.Chem.Soc. 136 11546 PMID: 25036716

Kvach et al (2009) Practical synthesis of isomerically pure 5- and 6-carboxytetramethylrhodamines, useful dyes for DNA probes. Bioconjug. Chem. 20 1673 PMID: 19606815

If you know of a relevant reference for 5-TAMRA SE, please let us know.

Keywords: 5-TAMRA SE, 5-TAMRA SE supplier, 5-TAMRASE, amine-reactive, yellow, fluorescent, labels, Telomerase, Fluorescent, Probes, Other, Standard, Fluorophores, 5441, Tocris Bioscience

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