Discontinued Product

5-TAMRA SE (Cat. No. 5441) has been withdrawn from sale for commercial reasons.
Cat.No. 5441 - 5-TAMRA SE | C29H25N3O7 | CAS No. 150810-68-7
Description: Orange fluorescent dye; supplied as NHS ester
Chemical Name: 5-Carboxytetramethylrhodamine succinimidyl ester
Purity: ≥95% (HPLC)
Protocols (1)
Literature (1)

Biological Activity

Fluorescent probe for DNA and RNA; amine-reactive. Also shown to stain telomeres. Nuclease resistant and nuclei permeable. Excitation\emission λ ~545\580 nm.

Optical Data for 5-TAMRA SE

Emission Color Orange
λabs 541 nm
λem 567 nm
Extinction Coefficient (ε) 84000 M-1cm-1
Quantum Yield (φ) 0.1
Closest Laser line 532 nm
Reactive Group NHS ester
Reactivity Primary amines
Correction Factor 260 0.32
Correction Factor 280 0.19
Alternative For Alexa Fluor(R) 546

Alexa Fluor® is a registered trademark of Molecular Probes, Inc, a Thermo Fisher Scientific Company.

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Technical Data

M. Wt 527.52
Formula C29H25N3O7
Storage Store at -20°C
Purity ≥95% (HPLC)
CAS Number 150810-68-7
PubChem ID 2762600
Smiles CN(C)C1=CC=C(C(C2=CC=C(C(ON3C(CCC3=O)=O)=O)C=C2C([O-])=O)=C(C=C/4)C(O5)=CC4=[N+](C)\C)C5=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.


References are publications that support the biological activity of the product.

Hirata et al (2014) Structural evaluation of tandem hairpin pyrrole-imidazole polyamides recognizing human telomeres. J.Am.Chem.Soc. 136 11546 PMID: 25036716

Kvach et al (2009) Practical synthesis of isomerically pure 5- and 6-carboxytetramethylrhodamines, useful dyes for DNA probes. Bioconjug. Chem. 20 1673 PMID: 19606815

Keywords: 5-TAMRA SE, 5-TAMRA SE supplier, 5-TAMRASE, amine-reactive, yellow, fluorescent, labels, Telomerase, Other, Fluorescent, Dyes, 5441, Tocris Bioscience

Citations for 5-TAMRA SE

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Currently there are no citations for 5-TAMRA SE.

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Protocols for 5-TAMRA SE

The following protocol features additional information for the use of 5-TAMRA SE (Cat. No. 5441).

Literature in this Area

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