HIV cell entry blocker. Binds gp120 and inhibits cell entry for a broad spectrum of HIV isolates. Exhibits no effect on the binding of CD4 or CCR5.
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
|ethanol||3.13||10mM with gentle warming|
Preparing Stock Solutions
The following data is based on the product molecular weight 313.33. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||3.19 mL||15.96 mL||31.92 mL|
|5 mM||0.64 mL||3.19 mL||6.38 mL|
|10 mM||0.32 mL||1.6 mL||3.19 mL|
|50 mM||0.06 mL||0.32 mL||0.64 mL|
References are publications that support the products' biological activity.
Herschhorn et al (2014) A broad HIV-1 inhibitor blocks envelope glycoprotein transitions critical for entry. Nat.Chem.Biol. 10 845 PMID: 25174000
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Keywords: 18A, supplier, Antivirals, Antivirals, Tocris Bioscience
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