New Products

View all new products by date added

Search for new products by date added, alphabetically, or by pharmacological action.

New products are an essential component of our range. Introductions are made on an ongoing basis, with hundreds of new small molecules and peptides being added every year. Our aim is to find the latest, otherwise unobtainable research tools, and bring them to the market as quickly as we can. New products can be identified throughout the Tocris website by the symbol.

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Cat. No. Product Name / Activity Date Added
8104 UH15-38 Apr 2024
Potent and selective RIPK3 inhibitor; also blocks activation of necroptosis
7828 HHP 9 Apr 2024
BET bromodomain Degrader (PROTAC®); also potent Hedgehog pathway inhibitor
8106 WNTinib Apr 2024
Inhibitor of mutant β-catenin signaling in hepatocellular carcinoma
8121 TRAM 1 Apr 2024
Chemical inducer of proximity for dTAG protein FKBPF36V and ecDHFR tags
8021 CST 626 Apr 2024
Potent pan IAP Degrader (PROTAC®)
8112 SLU-PP-332 Apr 2024
Potent pan-ERR agonist
7901 tri-GalNAc-C5-AF647 Apr 2024
Fluorescent ASGPR ligand. Application: flow cytometry, fluorescence microscopy
7973 5-InoAz Mar 2024
Metabolic probe for labeling mycobacterium cell envelope
3180 α-Cyclodextrin Mar 2024
Cyclic complexing agent
7903 VL 285 Mar 2024
VHL inhibitor
7985 BDY FL Staurosporine Mar 2024
Fluorescent probe targeting kinases; kinase tracer for TR-FRET assays
7927 MSC 1186 Mar 2024
Potent and selective SRPK family inhibitor
8101 dTAG Janelia Fluor® 635 Mar 2024
Fluorogenic srTAG probe for live cell imaging of FBKP12 (F36V/L) labelled proteins.
8066 CST 530, Phenol Mar 2024
Functionalized IAP ligand for PROTACs®
7890 CBMR 0083 Mar 2024
Potent allosteric FFA1 (GPR40) and 4 (GPR120) agonist
8051 Yoda 2 Feb 2024
Piezo1 channel activator
8041 α-Synuclein Degrader 2bn Feb 2024
Negative control for α Synuclein Degrader 2b (Cat. No. 8040)
7857 BDY FL Lenalidomide Feb 2024
Fluorescent cereblon ligand
8108 CEP Feb 2024
Chemoproteomic reagent, clickable electrophilic purine for RNA binding profiling in live cells
8011 FAI Feb 2024
Reagent for RNA SHAPE-MaP experiments in live cells
7983 IRAK3 Degrader 23 Feb 2024
IRAK3 PROTAC® Degrader
7998 PAG 4'-piperazine Feb 2024
Functionalized cereblon ligand for PROTAC development
7937 Trofinetide Feb 2024
IGF-1 synthetic analogue
8040 α-Synuclein Degrader 2b Jan 2024
α-synuclein Degrader (PROTAC®)
8063 CHDI 113 Jan 2024
Potent HTT pre-RNA splicing modulator
8098 ProtiFect STAR™ Protein Transfection Reagent Jan 2024
Protein transfection reagent
7847 Klotho-derived peptide 6 Jan 2024
Wnt/β-catenin signaling inhibitor
7851 EM 12-FS Jan 2024
Molecular glue; induces degradation of NQAT1
7891 Gilteritinib Jan 2024
Potent FLT3 inhibitor; also potently inhibits AXL
8013 RMR-Tre Jan 2024
Far-red fluorogenic trehalose probe for live mycobacteria imaging
7787 Ortho AP 1867 Jan 2024
Selective binding ligand for FKBP12F36V; precursor for dTAG compounds
7963 PFI 653 Jan 2024
Potent and selective vanin 1 inhibitor
7886 HER2 PROTAC® CH7C4 Jan 2024
Potent and selective HER2 targeting Degrader (PROTAC®)
7829 Thalidomide 4'-ether-alkylC6-azide Jan 2024
Cereblon ligand with alkyl linker and terminal azide for onward chemistry
7999 PAG 4'-piperazine-4-methylpiperidine Jan 2024
Cereblon ligand with terminal piperidine for onward chemistry
7719 TH 9619 disodium salt Jan 2024
MTHFD2 inhibitor
7969 SIS17 Jan 2024
Selective HDAC11 inhibitor
8042 Alkyne-cRGD Jan 2024
Integrin ligand for degrader development and targeted delivery, with alkyne click handle for conjugation
8029 JNJ 1013 Jan 2024
Interleukin 1 Receptor Associated Kinase 1 (IRAK1) Degrader (PROTAC®)
7830 Klotho-derived peptide 1 Jan 2024
TGF-β receptor 2 (TβR2) binding peptide; disrupts the TGF-β/TβR2 interaction
8100 Tocriscreen GPCR Compound Library Jan 2024
A bioactive compound library of 240 GPCR compounds (100 μL 10 mM DMSO solutions) for high-throughput screening, high-content screening, target validation and assay development
7950 CoraFluor™ 2, amine reactive Jan 2024
Terbium cryptate FRET donor for TR-FRET assay development; amine reactive for conjugation
7876 PZ 3022 Jan 2024
PanK Activator
7958 QM-FN-SO3 Jan 2024
Brain penetrant, NIR aggregation-induced emission active probe for in vivo imaging of Aβ plaques
8088 NICE 01 Dec 2023
Heterobifunctional compound for nuclear import of FKBPF36V tagged proteins
7982 CS 640 Dec 2023
Potent CaM kinase I inhibitor
8036 TDI 11861 Dec 2023
Soluble adenylyl cyclase inhibitor
7980 MTK 458 Dec 2023
PINK1 activator
7642 Dihydroethidium Dec 2023
Fluorescent ROS indicator
7394 Cy5B-trisulfo, NHS Dec 2023
Restricted conformation cyanine dye with high quantum yield and long fluorescence lifetime for advanced microscopy applications
7179 DOTAP Dec 2023
Cationic agent for liposome and LNP formation
7956 VU 0546110 Dec 2023
Selective SLO3 potassium channel inhibitor
7831 AUNP 12 Nov 2023
Peptide inhibitor of the PD-1 signaling pathway
6207 AP 1867 Nov 2023
Selective binding ligand for FKBP12F36V
3181 β-Cyclodextrin Nov 2023
Cyclic complexing agent
8005 PROTAC®(H-PGDS)-8 Nov 2023
Negative control for PROTAC®(H-PGDS)-7 (Cat. No. 8004)
8004 PROTAC®(H-PGDS)-7 Nov 2023
Potent hematopoietic prostaglandin D2 synthase Degrader (PROTAC®)
7852 EM12-SO2F Nov 2023
Potent covalent inhibitor of Cereblon
7981 Belinostat Oct 2023
Potent pan-HDAC inhibitor
7814 Tricyclic cytosine tC Oct 2023
Fluorescent tricyclic cytosine analog for RNA imaging
7865 AMG 900 Oct 2023
Potent pan-Aurora kinase inhibitor