New Products

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Search for new products by date added, alphabetically, or by pharmacological action.

New products are an essential component of our range. Introductions are made on an ongoing basis, with hundreds of new small molecules and peptides being added every year. Our aim is to find the latest, otherwise unobtainable research tools, and bring them to the market as quickly as we can. New products can be identified throughout the Tocris website by the symbol.

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Cat. No. Product Name / Activity Date Added
7544 SiRA 2 Jun 2024
Fluorogen for SiRA light-up aptamer. Application: confocal microscopy, SRM (including STED)
8119 ML T7 Jun 2024
Inhibitor of phosphatidylserine/CEACAM1 binding to Tim-3
8059 BTD S-sulfenic acid probe Jun 2024
Chemoproteomic reagent for targeting S-sulfenic acids on SulfenQ platform, alkyne handle for click chemistry
8094 Ac2-26 (Scrambled) Jun 2024
Negative control for Ac2-26 (Cat. No. 1845).
8123 VH 032 amide-PEG3-BCN Jun 2024
Functionalized VHL building block for copper-free click chemistry
8070 DX3-213B Jun 2024
Potent NDUFS7 antagonist
8055 VU 6019650 Jun 2024
M5 receptor antagonist
TB1126-RMU Dexamethasone Jun 2024
Dexamethasone synthesized to Ancillary Material Grade
8085 JPS036 Jun 2024
Selective HDAC3 Degrader (PROTAC®)
7979 MU 1742 Jun 2024
Potent and selective CK1α, CK1δ and CK1ε inhibitor
7556 ALDH Detection Reagent - BAAA-DA Jun 2024
Fluorescent ALDH substrate and detection reagent. Used for: identification of cells with high ALDH activity. Application: flow cytometry, fluorescent-activated cell sorting (FACS)
8050 SA-15-P Jun 2024
Dual inhibitor of LAG3 interaction with both MHCII and FGL1
7996 PAG 3'-piperazine Jun 2024
Functionalized cereblon ligand for PROTAC development
7913 Pomalidomide 5'-piperidine-acid Jun 2024
Cereblon ligand with piperidine linker and terminal acid for onward chemistry
7941 FSEN 1 May 2024
Induces ferroptosis; inhibits FSP1
1472 Suramin hexasodium salt May 2024
Non-selective P2 antagonist
8027 Janelia Fluor® 635, Maleimide May 2024
Red dye (Reactive group: maleimide). Application: flow cytometry, confocal microscopy, super resolution microscopy. Suitable for live cell imaging
7994 PAG 3'-fluoro-4'-piperazine May 2024
Functionalized cereblon ligand for PROTAC development
7769 Chem-CLIP control probe May 2024
Control probe for Chem-CLIP experiments
8105 CAF 382 May 2024
Potent and selective CDKL5 inhibitor
8109 MYX 1715 May 2024
N-myristoyltransferase (NMT) inhibitor
7990 NRX 252114 May 2024
Molecular glue Degrader of mutant β-catenin
7753 BL660-NO May 2024
Nitric oxide activity-based sensing NIR bioluminescent probe
7808 NDT 30805 May 2024
Potent NLRP3 inflammasome inhibitor
8120 NVS-STG2 May 2024
STING agonist, molecular glue that causes oligomerization of STING
7801 CST 967 May 2024
Potent and selective USP7 Degrader (PROTAC®)
7570 T3 CLK Apr 2024
Potent and selective pan-CLK inhibitor; also inhibits DYRK1A/B
TB3222-RMU TCS JNK 6o Apr 2024
TCS JNK 6o synthesized to Ancillary Material Grade
8104 UH15-38 Apr 2024
Potent and selective RIPK3 inhibitor; also blocks activation of necroptosis
7828 HHP 9 Apr 2024
BET bromodomain Degrader (PROTAC®); also potent Hedgehog pathway inhibitor
8106 WNTinib Apr 2024
Inhibitor of mutant β-catenin signaling in hepatocellular carcinoma
8121 TRAM 1 Apr 2024
Chemical inducer of proximity for dTAG protein FKBPF36V and ecDHFR tags
8112 SLU-PP-332 Apr 2024
Potent pan-ERR agonist
8021 CST 626 Apr 2024
Potent pan IAP Degrader (PROTAC®)
7901 tri-GalNAc-C5-AF647 Apr 2024
Fluorescent ASGPR ligand. Application: flow cytometry, fluorescence microscopy
7973 5-InoAz Mar 2024
Metabolic probe for labeling mycobacterium cell envelope
7903 VL 285 Mar 2024
VHL inhibitor
7985 BDY FL Staurosporine Mar 2024
Fluorescent probe targeting kinases; kinase tracer for TR-FRET assays
7927 MSC 1186 Mar 2024
Potent and selective SRPK family inhibitor
8101 dTAG Janelia Fluor® 635 Mar 2024
Fluorogenic srTAG probe for live cell imaging of FBKP12 (F36V/L) labelled proteins.
8066 CST 530, Phenol Mar 2024
Functionalized IAP ligand for PROTACs®
7890 CBMR 0083 Mar 2024
Potent allosteric FFA1 (GPR40) and 4 (GPR120) agonist
3180 α-Cyclodextrin Mar 2024
Cyclic complexing agent
7857 BDY FL Lenalidomide Feb 2024
Fluorescent cereblon ligand
8108 CEP Feb 2024
Chemoproteomic reagent, clickable electrophilic purine for RNA binding profiling in live cells
8051 Yoda 2 Feb 2024
Piezo1 channel activator
8041 α-Synuclein Degrader 2bn Feb 2024
Negative control for α Synuclein Degrader 2b (Cat. No. 8040)
8011 FAI Feb 2024
Reagent for RNA SHAPE-MaP experiments in live cells
7983 IRAK3 Degrader 23 Feb 2024
IRAK3 Degrader (PROTAC®
7998 PAG 4'-piperazine Feb 2024
Functionalized cereblon ligand for PROTAC development
7937 Trofinetide Feb 2024
IGF-1 synthetic analogue
8063 CHDI 113 Jan 2024
Potent HTT pre-RNA splicing modulator
8040 α-Synuclein Degrader 2b Jan 2024
α-synuclein Degrader (PROTAC®)
8098 ProtiFect STAR™ Protein Transfection Reagent Jan 2024
Protein transfection reagent
7847 Klotho-derived peptide 6 Jan 2024
Wnt/β-catenin signaling inhibitor
7787 Ortho AP 1867 Jan 2024
Selective binding ligand for FKBP12F36V; precursor for dTAG compounds
7891 Gilteritinib Jan 2024
Potent FLT3 inhibitor; also potently inhibits AXL
7963 PFI 653 Jan 2024
Potent and selective vanin 1 inhibitor
7851 EM 12-FS Jan 2024
Molecular glue; induces degradation of NQAT1
8013 RMR-Tre Jan 2024
Far-red fluorogenic trehalose probe for live mycobacteria imaging
7886 HER2 PROTAC® CH7C4 Jan 2024
Potent and selective HER2 targeting Degrader (PROTAC®)
7829 Thalidomide 4'-ether-alkylC6-azide Jan 2024
Cereblon ligand with alkyl linker and terminal azide for onward chemistry
7719 TH 9619 disodium salt Jan 2024
MTHFD2 inhibitor
7999 PAG 4'-piperazine-4-methylpiperidine Jan 2024
Cereblon ligand with terminal piperidine for onward chemistry
7969 SIS17 Jan 2024
Selective HDAC11 inhibitor
8029 JNJ 1013 Jan 2024
Interleukin 1 Receptor Associated Kinase 1 (IRAK1) Degrader (PROTAC®)
7830 Klotho-derived peptide 1 Jan 2024
TGF-β receptor 2 (TβR2) binding peptide; disrupts the TGF-β/TβR2 interaction
7876 PZ 3022 Jan 2024
PanK Activator
7950 CoraFluor™ 2, amine reactive Jan 2024
Terbium cryptate FRET donor for TR-FRET assay development; amine reactive for conjugation
8042 Alkyne-cRGD Jan 2024
Integrin ligand for degrader development and targeted delivery, with alkyne click handle for conjugation
8100 Tocriscreen GPCR Compound Library Jan 2024
A bioactive compound library of 240 GPCR compounds (100 μL 10 mM DMSO solutions) for high-throughput screening, high-content screening, target validation and assay development
7958 QM-FN-SO3 Jan 2024
Blood-brain barrier penetrant, NIR aggregation-induced emission active probe of amyloid β plaques. Used for: in vitro, in situ and in vivo imaging of amyloid β plaques. Application: confocal microscopy and in vivo imaging