Neuromedin U Receptors

Supporting information

Neuromedin U (NMU) receptors are a group of Gq/11-protein-coupled receptors that are currently divided into two subtypes: NMU1 and NMU2. The two subtypes have distinct tissue distributions: NMU1 is expressed in the periphery (especially in the gastrointestinal tract), whilst NMU2 is expressed in the central nervous system (especially in the substantia nigra, medulla oblongata and pontine reticular formation).

NMU receptors mediate diverse biological effects including contraction of the uterus, peripheral vasoconstriction causing hypertension and activation of the HPA axis resulting in decreased food intake via the CRH system. The human genes encoding NMU1 and NMU2 are located on chromosomes 2q37.1 and 5q33.1 respectively.

To view external sources of pharmacological information for Neuromedin U Receptors, please click here: IUPHAR Receptor Code and BJP Guide

View all products for Neuromedin U Receptors »
Gene Species Gene Symbol Gene Accession No. Protein Accession No.
NMU1 Human NMUR1 NM_006056 Q9HB89
Mouse Nmur1 NM_010341 O55040
Rat Nmur1 NM_023100 Q9JJI5
NMU2 Human NMUR2 NM_020167 Q9GZQ4
Mouse Nmur2 NM_153079 Q8BZ39
Rat Nmur2 NM_022275 Q9ESQ4

Literature for Neuromedin U Receptors

GPCR Product Listing

A collection of over 450 products for G protein-coupled receptors, the listing includes research tools for the study of:

  • Rhodopsin-like Receptors
  • Secretin-like Receptors
  • Glutamate Receptors
  • Frizzled Receptors
  • GPCR Signaling
Request copy | Download PDF | View all Product Guides & Listings
GPCR Product Listing
Peptide Hormone Receptors Product Listing

A collection of over 200 products for peptide hormone receptors, the listing includes research tools for the study of:

  • Anterior Pituitary Regulation
  • Blood Pressure Regulation
  • Feeding and Appetite Regulation
  • Glucose Regulation
  • Peptide Hormone Processing
Request copy | Download PDF | View all Product Guides & Listings
Peptide Hormone Receptors Product Listing

Quick Order

Find multiple products by catalog number

divider line

Peptide Hormone Receptors Product Listing

Peptide Hormone Receptors Product Listing

Our Peptide Hormone Receptors Listing highlights over 200 products for peptide hormone receptors. Request copy or view PDF today.

divider line

GPCR Product Listing

GPCR Product Listing

Highlights over 450 products for GPCRs. Request copy or view PDF today.

divider line

Bio-Techne Events

SENC 2017

17th National Congress of the Spanish Society of Neuroscience

September 27 - 30, 2017

Alicante, Spain