Sensory Neuron-Specific Receptors

Supporting information

Sensory Neuron-Specific Receptors (SNSRs) are a newly identified group of G-protein-coupled receptors that are exclusively localized in a subset of small dorsal root and trigeminal sensory neurons. SNSRs are involved in pain modulation, but their precise mechanism of action has not yet been eluded as rodent orthologs have yet to be clearly defined. Proposed actions include modulation of neuronal calcium and potassium channels and inhibition of presynaptic firing.

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Gene Species Gene Symbol Gene Accession No. Protein Accession No.
SNSR1 Human MRGPRX3 NM_054031 Q96LB0
SNSR4 Human MRGPRX1 NM_147199 Q96LB2
Mouse Mrgprx1 NM_207540 Q8CIP3
Rat Mrgprx1 NM_172158 Q8R4G1
SNSR6 Human MRGPRX4 NM_054032 Q96LA9

Literature for Sensory Neuron-Specific Receptors

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