Monoamine Oxidases

Supporting information

Monoamine Oxidases (MAO) catalyze the oxidation of monoamines such as dopamine, serotonin and adrenalin. They are found bound to the outer membrane of mitochondria in most cell types in the body. Two subtypes of monoamine oxidase have been identified: MAO-A and MAO-B. Both are found in neurons and astroglia, with MAO-A also found in the liver, gastrointestinal tract and placenta and MAO-B in blood platelets. Abnormal regulation of MAOs in the body has been associated with depression, substance abuse, attention deficit disorder, and irregular sexual maturation.

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Gene Species Gene Symbol Gene Accession No. Protein Accession No.
MAO-A Human MAOA NM_000240 P21397
Mouse Maoa NM_173740 Q64133
Rat Maoa XM_343764 P21396
MAO-B Human MAOB NM_000898 P27338
Mouse Maob NM_172778 Q8BW75
Rat Maob NM_013198 P19643

Literature for Monoamine Oxidases

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