Adenylyl Cyclases

More Information »Adenylyl Cyclases (AC) are a group of enzymes that convert adenosine-5'-triphosphate (ATP) into 3',5'-adenosine monophosphate (cyclic AMP/cAMP) and pyrophosphate. There are ten different mammalian isoforms of adenylyl cylase; nine of which are membrane-bound.

Adenylyl Cyclase Products

Product Name / Activity
3635 BPIPP
Non-competitive AC inhibitor. Also GC inhibitor
3834 KH 7
Selective soluble adenylyl cyclase inhibitor
1436 MDL 12330A hydrochloride
Adenylyl cyclase inhibitor; also cyclic nucleotide PDE inhibitor
5071 NKY 80
Adenylyl cyclase inhibitor
1586 SKF 83566 hydrobromide
Selectively inhibits AC2; also a potent, selective D1-like antagonist
1435 SQ 22536
Adenylyl cyclase inhibitor
6271 ST 034307
Adenylyl cyclase 1 (AC1) inhibitor; analgesic and active in vivo
Product Name / Activity
1099 Forskolin
Adenylyl cyclase activator
1603 NKH 477
Water-soluble adenylyl cyclase activator
1183 PACAP 1-27
Potently stimulates adenylyl cyclase
1186 PACAP 1-38
Potently stimulates adenylyl cyclase
Ligand Sets
Product Name / Activity
1882 PKA Tocriset™
Selection of 5 PKA modulators (Cat. Nos. 1337, 1140, 1099, 1288 and 1603)
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