σ2 Receptors

More Information »σ2 receptors are members of the sigma (σ) family of receptors that also includes σ1 receptors. Originally thought to be opioid receptors or the phencyclidine binding site on the NMDA receptor, they are now know to be distinct targets. They are distributed throughout the CNS.

σ2 Receptor Products

Agonists
Cat.No.
Product Name / Activity
2562 PB 28 dihydrochloride
High affinity σ2 agonist
Antagonists
Cat.No.
Product Name / Activity
1497 Rimcazole dihydrochloride
σ2 antagonist. Also DAT inhibitor
0751 SM-21 maleate
Selective σ2 antagonist. Centrally active
Ligands
Cat.No.
Product Name / Activity
0545 Ifenprodil hemitartrate
σ ligand (σ2 > σ1). Also α1 antagonist and NMDA antagonist acting at polyamine site
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