Ack1

More Information »Activated Cdc42-associated kinase 1 (Ack1, E.C. 2.7.10.2), also known as TNK2, is a 114 kDa member of the Ack family of mammalian non-receptor tyrosine kinases (NRTKs) which is activated by multiple receptor tyrosine kinases (RTKs) to perform various roles within the cell.

Ack1 Products

Inhibitors
Cat.No.
Product Name / Activity
4946 AIM 100
Potent and selective Ack1 (TNK2) inhibitor
5310 ASP 3026
Potent Ack (TNK2) inhibitor; also inhibits anaplastic lymphoma kinase (ALK)
5607 GNF 7
Ack1 and GCK inhibitor; inhibits Ras signaling
5098 KRCA 0008
Potent Ack1 and ALK dual inhibitor; orally bioavailable
6061 XMD 8-87
Potent Ack1/TNK2 inhibitor
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