NOP Receptors

More Information »The NOP receptor, (also known as ORL1, N/OFQ receptor), is a member of the opioid family of G-protein-coupled receptors that also includes κ, δ and μ receptors. The human gene encoding the NOP receptor has been localized to chromosome 20 (20q13.33).

NOP Receptor Products

Product Name / Activity
3763 MCOPPB trihydrochloride
Potent NOP receptor agonist
1780 NNC 63-0532
Potent non-peptide NOP agonist; brain penetrant
0910 Nociceptin
Endogenous NOP agonist
1358 Nociceptin (1-13)NH2
Potent ORL1 agonist
1590 [Arg14,Lys15]Nociceptin
Highly potent and selective NOP agonist
1566 [(pF)Phe4]Nociceptin(1-13)NH2
Potent, selective nociceptin receptor agonist
1092 [Phe1Ψ(CH2-NH)Gly2]Nociceptin(1-13)NH2
Selective nociceptin receptor agonist
3932 Orphanin FQ (1-11)
Potent NOP agonist; displays analgesic properties
1387 Ac-RYYRWK-NH2
Potent, selective NOP partial agonist peptide
3240 SCH 221510
Potent and selective NOP agonist
Product Name / Activity
3661 BAN ORL 24
Potent and selective NOP antagonist
2598 (±)-J 113397
Potent and selective NOP antagonist
2481 JTC 801
Selective NOP antagonist
1308 [Nphe1]Nociceptin(1-13)NH2
Selective, competitive nociceptin antagonist
1118 Nocistatin (bovine)
Opposes action of nociceptin
1198 Nocistatin (human)
Human putative counterpart of nocistatin
3573 SB 612111 hydrochloride
Selective NOP receptor antagonist
2508 Trap 101
Potent and selective NOP antagonist; active in vivo
1552 UFP-101
Potent, selective silent antagonist for NOP
Product Name / Activity
1239 Ac-RYYRIK-NH2
High affinity NOP ligand
Product Name / Activity
1266 Nociceptin (1-7)
Bioactive metabolite of nociceptin
1119 NocII
Orphan neuropeptide
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