κ Opioid Receptors

More Information »The κ opioid receptor, (also known as OP2, KOP, KOR), is a member of the opioid family of G-protein-coupled receptors that also includes μ, δ and NOP receptors. Three variants of the receptor (designated κ1, κ2, and κ3) have been characterized.

κ Opioid Receptor Products

Agonists
Cat.No.
Product Name / Activity
0699 BRL 52537 hydrochloride
Potent and selective κ agonist
3195 Dynorphin A
Endogenous κ agonist
3196 Dynorphin B
Endogenous κ agonist
2962 6'-GNTI dihydrochloride
Selective κ/δ opioid heterodimer receptor agonist
1483 GR 89696 fumarate
Subtype-selective κ agonist
0778 ICI 199,441 hydrochloride
Potent κ agonist
0822 ICI 204,448 hydrochloride
κ agonist, acts peripherally
0783 N-MPPP Hydrochloride
Selective κ agonist
5519 (-)-Pentazocine
κ-agonist; antinociceptive
2134 Salvinorin A
Highly potent and selective κ agonist
0496 (-)-U-50488 hydrochloride
Standard selective κ agonist. More active enantiomer of (±)-U-50488 (Cat. No. 0495)
0471 (+)-U-50488 hydrochloride
Standard selective κ agonist. Less active enantiomer of (±)-U-50488 (Cat. No. 0495)
0495 (±)-U-50488 hydrochloride
Standard selective κ agonist
0498 U-54494A hydrochloride
κ agonist
Antagonists
Cat.No.
Product Name / Activity
0347 nor-Binaltorphimine dihydrochloride
Standard κ selective antagonist
0794 DIPPA hydrochloride
Selective irreversible κ antagonist
1282 GNTI dihydrochloride
Potent, selective κ antagonist
4866 ML 190
Selective κ opioid receptor antagonist
Other
Cat.No.
Product Name / Activity
5611 Salvinorin B
Activates the κ-opioid DREADD (KORD)
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