μ Opioid Receptors

Supporting information

The μ opioid receptor, (also known as OP3, MOP, MOR), is a member of the opioid family of G-protein-coupled receptors that also includes κ, δ and NOP receptors. Three variants of the receptor (designated μ1, μ2 and μ3) have been characterized, arising from the alternative splicing of the this gene.

μ Opioid receptors are distributed throughout the neuraxis (neocortex, thalamus, nucleus accumbens, hippocampus, amygdala) and in the peripheral nervous system (myenteric neurons and vas deferens). μ opioid receptors have been implicated in respiration, cardiovascular functions, feeding, learning and memory, intestinal transit, locomotor activity, thermoregulation, hormone secretion and immune functions. The human gene encoding the μ opioid receptor has been localized to chromosome 6 (6q24-q25).

To view external sources of pharmacological information for μ Opioid Receptors, please click here: IUPHAR Receptor Code and BJP Guide

View all products for μ Opioid Receptors »
Species Gene Symbol Gene Accession No. Protein Accession No.
Human OPRM1 NM_000914 P35372
Mouse Oprm1 NM_001039652 P42866
Rat Oprm1 NM_013071 P33535

Literature for μ Opioid Receptors

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