Tocriscreen Compound Libraries

Supporting information

The Tocriscreen compound libraries are composed of biologically active compounds that have proven pharmacological activity against GPCRs, ion channels, kinases, enzymes, nuclear receptors and transporters.

The new Tocriscreen Plus extends the range of targets to over 300 and includes new compounds for studying epigenetics and stem cell biology. This library has been designed for screening assays based on chemical genetics, chemical biology, receptor de-orphaning, target validation or drug re-profiling. Comprised of biologically active compounds selected from the Tocris catalog, Tocriscreen libraries provide wide coverage of the most important targets covered in biochemical and cellular screening assays.

For a full list of the compounds available in Tocriscreen Plus, please complete our compound library enquiry form.

Graphs for Tocriscreen Plus Target Coverage

GPCRs

Tocriscreen PLUS contains 349 compounds that target 98 different GPCRs. Click on the graph for an overview of the GPCRs covered.

Graph showing GPCRs targeted by products in Tocriscreen PLUS
Kinases

Tocriscreen PLUS contains 253 compounds that target over 60 different kinases and enzyme-linked receptors. Click on the graph for an overview of the kinases covered.

Graph showing kinases targeted by products in Tocriscreen PLUS
Enzymes (Non-Kinase)

Tocriscreen PLUS contains 241 compounds that target 68 different enzymes not included in the kinase group. Click on the graph for an overview of the enzymes covered.

Graph showing enzymes (non-kinases) targeted by products in Tocriscreen PLUS
Ion Channels

Tocriscreen PLUS contains 177 compounds that target 28 different ion channels, including both voltage-gated and ligand-gated channels. Click on the graph for an overview of the ion channels covered.

Graph showing ion channels targeted by products in Tocriscreen PLUS
Nuclear Receptors

Tocriscreen PLUS contains 69 compounds that target 17 nuclear receptors from different classes. Click on the graph for an overview of the nuclear receptors covered.

Graph showing nuclear receptors targeted by products in Tocriscreen PLUS
Transporters

Tocriscreen PLUS contains 48 compounds that target 16 neurotransmitter, multidrug receptor and ion transporters. Click on the graph for an overview of the transporters covered.

Graph showing transporters targeted by products in Tocriscreen PLUS
View all products for Tocriscreen Compound Libraries »

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New Product Guide (Fall/Winter 2016)

Our New Product guide highlights over 100 new products added in the second half of 2016. Request copy or view PDF today.

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