Dopamine Transporters

More Information »Dopamine transporters (DAT) are sodium- and chloride-dependent members of the solute carrier family 6 (SLC6) widely distributed throughout the brain in areas of dopaminergic activity, including the striatum and substantia nigra. They provide rapid clearance of dopamine.

Dopamine Transporter Products

Product Name / Activity
4357 Bicifadine hydrochloride
Noradrenalin, 5-HT and dopamine re-uptake inhibitor
0918 3α-Bis-(4-fluorophenyl) methoxytropane hydrochloride
Potent dopamine uptake inhibitor
0702 BTCP maleate
Potent dopamine uptake inhibitor
2831 Bupropion hydrochloride
Non-selective inhibitor of dopamine and noradrenalin transporters
2833 Cocaine hydrochloride
Inhibitor of monoamine transporters
0917 3-CPMT
Dopamine uptake inhibitor
4798 (S)-Duloxetine hydrochloride
Potent 5-HT and NA reuptake inhibitor; also blocks dopamine reuptake
0513 GBR 12783 dihydrochloride
Potent, selective dopamine uptake inhibitor
0421 GBR 12909 dihydrochloride
Selective DA uptake inhibitor. Also σ ligand
0514 GBR 12935 dihydrochloride
Selective dopamine uptake inhibitor
0420 GBR 13069 dihydrochloride
Potent dopamine uptake inhibitor
1588 Indatraline hydrochloride
Potent dopamine uptake inhibitor; also inhibits 5-HT and noradrenalin uptake
4351 JHW 007 hydrochloride
High affinity dopamine uptake inhibitor
2148 (±)-McN 5652
Potent, orally active 5-HT uptake inhibitor. Also inhibits noradrenalin and dopamine uptake in vitro
3027 (±)-MDMA hydrochloride
Inhibitor of dopamine and 5-HT uptake; hallucinogenic
4443 Mephedrone hydrochloride
Inhibits synaptosomal dopamine and 5-HT uptake
1812 Threo-methylphenidate hydrochloride
Inhibitor of dopamine and noradrenalin transporters. Psychomotor stimulant
6131 (R)-Modafinil
Dopamine uptake inhibitor
1992 Nomifensine
Potent noradrenalin and dopamine uptake inhibitor. Antidepressant
2742 Reserpine
Inhibitor of vesicular monoamine transport
1497 Rimcazole dihydrochloride
DAT inhibitor. Also σ2 antagonist
2175 Tetrabenazine
Potent inhibitor of vesicular monoamine transport; depletes dopamine stores
Product Name / Activity
5200 FFN 102 mesylate
Selective fluorescent substrate of DAT and VMAT2
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