D4 Receptors

Supporting information

D4 receptors are members of the dopamine receptor G-protein-coupled receptor family that also includes D1, D2, D3 and D5. They are located primarily in the frontal cortex, midbrain, amygdala and the cardiovascular system. The function of the D4 receptor is unknown, although a role in cognition and emotion has been proposed. The human D4 receptor gene has been localized to chromosome 11 (11q15.5).

To view external sources of pharmacological information for D4 Receptors, please click here: IUPHAR Receptor Code and BJP Guide

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Species Gene Symbol Gene Accession No. Protein Accession No.
Human DRD4 NM_000797 P21917
Mouse Drd4 NM_007878 P51436
Rat Drd4 NM_012944 P30729

Literature for D4 Receptors

GPCR Product Listing

A collection of over 450 products for G protein-coupled receptors, the listing includes research tools for the study of:

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  • Secretin-like Receptors
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Dopamine Receptors Scientific Review

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Dopamine Receptors Scientific Review
Addiction Life Science Poster

Written by Prof David Nutt, this poster summarizes the brain circuits associated with addiction and outlines the main classes of addictive drugs and neurotransmitter systems affected by them. Compounds available from Tocris for addiction research are listed.

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Addiction Life Science Poster
Parkinson's Life Science Poster

Written by Anthony H.V. Schapira, this poster summarizes the neurobiology of Parkinson's disease (PD), including new genetic insight, neurotransmitter pathways, and the role of aberrant α-synuclein metabolism in PD pathogenesis. This poster also presents new and emerging therapeutic strategies to delay the onset and progress of PD. Compounds available from Tocris are listed.

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Parkinson's Life Science Poster

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GPCR Product Listing

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Dopamine Review

Written by P. Strange & K.Neve

Dopamine Receptors Scientific Review

Our Dopamine receptors review gives an overview of the dopamine receptor subtypes, and the receptor agonists and antagonists used to study them. Request copy or view PDF today.

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Mechanisms of Addiction

Addiction Life Science Poster

Written by Prof David Nutt, this poster summarizes the brain circuits and neurotransmitter systems that are affected by the main classes of addictive drugs. Request copy or view PDF today.

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Parkinson's disease: Neurobiology and Therapeutic Strategies

Written by Anthony H.V. Schapira

Parkinson's Life Science Poster

Our Parkinson's disease (PD) poster summarizes the neurobiology of the disease, and highlights current therapeutic treatments for symptomatic PD. Request copy or view PDF today.

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