D4 Receptors

More Information »D4 receptors are members of the dopamine receptor G-protein-coupled receptor family that also includes D1, D2, D3 and D5. They are located primarily in the frontal cortex, midbrain, amygdala and the cardiovascular system. A role in cognition and emotion has been proposed.

D4 Receptor Products

Product Name / Activity
4552 A 412997 dihydrochloride
Selective D4 agonist
2214 ABT 724 trihydrochloride
Potent, selective D4 partial agonist; proerectile
1065 PD 168077 maleate
High affinity, selective D4 agonist
2329 Ro 10-5824 dihydrochloride
Selective D4 receptor partial agonist
4380 WAY 100635 maleate
Dopamine D4 agonist. Also 5-HT1A silent antagonist
Product Name / Activity
2645 Fananserin
D4 antagonist. Also 5-HT2A antagonist
1004 L-741,742 hydrochloride
Highly selective D4 antagonist
1002 L-745,870 trihydrochloride
Highly selective D4 antagonist
3529 PD 168568 dihydrochloride
Potent and selective D4 antagonist
2735 PNU 96415E
D4 and 5-HT2A antagonist; antipsychotic
4185 Sonepiprazole
Selective D4 receptor antagonist
Product Name / Activity
3298 NGD 94-1
Selective D4 receptor ligand
Related Categories

Quick Order

Find multiple products by catalog number

divider line

GPCR Product Listing

GPCR Product Listing

Highlights over 450 products for GPCRs. Request copy or view PDF today.

divider line

Dopamine Review

Written by P. Strange & K.Neve

Dopamine Receptors Scientific Review

Our Dopamine receptors review gives an overview of the dopamine receptor subtypes, and the receptor agonists and antagonists used to study them. Request copy or view PDF today.

divider line

Mechanisms of Addiction

Addiction Life Science Poster

Written by Prof David Nutt, this poster summarizes the brain circuits and neurotransmitter systems that are affected by the main classes of addictive drugs. Request copy or view PDF today.

divider line

Parkinson's disease: Neurobiology and Therapeutic Strategies

Written by Anthony H.V. Schapira

Parkinson's Life Science Poster

Our Parkinson's disease (PD) poster summarizes the neurobiology of the disease, and highlights current therapeutic treatments for symptomatic PD. Request copy or view PDF today.

divider line

LinkedIn Updates

Follow Tocris on LinkedIn

Follow us on LinkedIn!

Visit our LinkedIn page for the latest Tocris news, events and updates.