D3 Receptors

More Information »D3 receptors are members of the dopamine receptor G-protein-coupled receptor family that also includes D1, D2, D4 and D5. They are located primarily in the nucleus accumbens, olfactory tubercle and island of Calleja where they are involved in the modulation of locomotion.

D3 Receptor Products

Product Name / Activity
0706 7-Hydroxy-DPAT hydrobromide
Dopamine agonist (D3 ≥ D2 < > D4)
0719 7-Hydroxy-PIPAT maleate
D3 agonist (D3 > D2)
1243 (+)-PD 128907 hydrochloride
D3 agonist (D3 ≥ D2 > D4)
4174 Pramipexole dihydrochloride
Selective D3 agonist
3896 Rotigotine hydrochloride
Dopamine D2/D3 agonist
Product Name / Activity
1847 Eticlopride hydrochloride
D3 antagonist (D3 > D2)
3940 GSK 789472 hydrochloride
D3 antagonist. Also D2 partial agonist
1347 Nafadotride
Highly potent, preferential D3 antagonist
2635 NGB 2904
Potent and selective D3 antagonist
3887 PG 01037 dihydrochloride
D3 receptor selective antagonist
3355 PNU 177864 hydrochloride
Highly selective D3 antagonist
4207 SB 277011A dihydrochloride
Selective D3 antagonist
1357 U 99194 maleate
Potent, selective D3 antagonist
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