Glutamate (Metabotropic) Group I Receptor Modulators

 
Cat.No.
Product Name / Activity
4416 ADX 10059 hydrochloride
Negative allosteric modulator at mGlu5
3235 CDPPB
Positive allosteric modulator at mGlu5
4787 CPPHA
Positive allosteric modulator at mGlu1 and mGlu5
1952 DCB
Allosteric modulator at mGlu5
1625 DFB
Allosteric potentiator at mGlu5
1953 DMeOB
Negative allosteric modulator at mGlu5
5000 FTIDC
Potent and selective negative allosteric modulator at mGlu1; also mGlu1 inverse agonist
5275 LSN 2463359
Potent and selective positive allosteric modulator at mGlu5
4438 MFZ 10-7
Negative allosteric modulator at mGlu5
4348 Ro 01-6128
Positive allosteric modulator of mGlu1
4347 Ro 67-4853
Positive allosteric modulator of group I mGlu receptors
4346 Ro 67-7476
Positive allosteric modulator of mGlu1
4381 VU 0285683
Negative allosteric modulator at mGlu5
4437 VU 0357121
Positive allosteric modulator of mGlu5
4323 VU 0360172 hydrochloride
Positive allosteric modulator at mGlu5
4394 VU 0360223
Negative allosteric modulator at mGlu5
5322 VU 0409106
Potent and selective negative allosteric modulator at mGlu5
5693 VU 0409551
Selective mGlu5 positive allosteric modulator; brain penetrant and orally bioavailable
5379 VU 0469650 hydrochloride
Potent and selective negative allosteric modulator of mGlu1
5377 VU 0483605
Positive allosteric modulator at mGlu1
3325 VU 1545
mGlu5 positive allosteric modulator
4458 VU 29
Potent mGlu5 allosteric potentiator

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