Kainate Receptors

Supporting information

Kainate receptors are members of the ionotropic class of glutamate receptors, which also includes NMDA and AMPA receptors. Kainate receptors have been identified both pre- and post-synaptically. The receptors contribute to excitatory postsynaptic currents in many regions of the CNS and play a role in short- and long-term synaptic plasticity. Kainate receptors consist of GluR5-7 and KA1-2 subunits. Each subunit has an extracellular N-terminus, a cytoplasmic C-terminus, three membrane-spanning segments and a p-loop that dips into the membrane from the cytoplasmic face to form the pore.

To view external sources of pharmacological information for Kainate Receptors, please click here: BJP Guide

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Gene Species Gene Symbol Gene Accession No. Protein Accession No.
GluK1 (formerly GluR5) Human GRIK1 NM_175611 P39086
Mouse Grik1 NM_146072 Q60934
Rat Grik1 NM_017241 P22756
GluK2 (formerly GluR6) Human GRIK2 NM_175768 Q13002
Mouse Grik2 NM_010349 P39087
Rat Grik2 NM_019309 P42260
View all Kainate Receptor Gene Data »

Literature for Kainate Receptors

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Pain Research Product Guide

Pain Research Product Guide

Our Pain guide highlights over 280 products for Pain research. Request copy or view PDF today.

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Learning and Memory

Written by Clea Warburton and Zafar Bashir

Learning & Memory Life Science Poster

Our Learning and Memory poster gives an overview of the cellular mechanisms underlying recognition memory and its links to long-term depression. Request copy or view PDF today.

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Addiction Life Science Poster

Written by Prof David Nutt, this poster summarizes the brain circuits and neurotransmitter systems that are affected by the main classes of addictive drugs. Request copy or view PDF today.

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Our Parkinson's disease (PD) poster summarizes the neurobiology of the disease, and highlights current therapeutic treatments for symptomatic PD. Request copy or view PDF today.

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