Adrenergic α1 Receptors

More Information »Adrenergic α1 receptors (α1-adrenoceptors) are members of the adrenergic receptor group of G-protein-coupled receptors that also includes α2A, α2B, α2C, β1, β2 and β3. The adrenergic α1 receptors are further divided into three subtypes: α1A, α1B and α1D receptors.

Adrenergic α1 Receptor Products

Agonists
Cat.No.
Product Name / Activity
1052 A 61603 hydrobromide
α1A agonist
0888 Cirazoline hydrochloride
Selective α1 agonist
1142 Oxymetazoline hydrochloride
α1A agonist
2838 (R)-(-)-Phenylephrine hydrochloride
α1 agonist
Antagonists
Cat.No.
Product Name / Activity
5940 AdTx1
Selective, high affinity, non-competitive α1A adrenoceptor antagonist
3305 Alfuzosin hydrochloride
Uroselective α1 antagonist
1006 BMY 7378 dihydrochloride
Selective α1D antagonist
2685 Carvedilol
α1 and β antagonist
2964 Doxazosin mesylate
α1 antagonist
0535 HEAT hydrochloride
Highly selective α1 antagonist
0545 Ifenprodil hemitartrate
α1 antagonist. Also NMDA antagonist and σ ligand
0661 2-MPMDQ
Potent, selective α1 antagonist. Also σ2 ligand
0597 Naftopidil hydrochloride
α1 antagonist
1124 (R)-(-)-Niguldipine hydrochloride
α1 antagonist, L-type Ca2+ channel blocker. Less active enantiomer of Niguldipine hydrochloride (Cat. No. 1123)
1123 (S)-(+)-Niguldipine hydrochloride
α1 antagonist, L-type Ca2+ channel blocker
0627 2-PMDQ
Potent, selective α1 antagonist
0623 Prazosin hydrochloride
α1 and α2B antagonist. MT3 antagonist
3284 Rec 15/2615 dihydrochloride
Selective α1B antagonist
1325 RS 100329 hydrochloride
Potent, subtype-selective α1A antagonist
0985 RS 17053 hydrochloride
α1A antagonist
2398 SNAP 5089
Subtype-selective α1A antagonist
3050 Tamsulosin hydrochloride
Selective α1A antagonist
1506 Terazosin hydrochloride
α1 and α2B antagonist (α1 > α2B). Orally active
1772 Urapidil hydrochloride
α1 antagonist. Also 5-HT1A receptor agonist
0946 WB 4101 hydrochloride
α1A antagonist
Ligand Sets
Cat.No.
Product Name / Activity
1871 α1-Adrenoceptor Tocriset™
Selection of 5 α1-adrenoceptor ligands (Cat. Nos. 1052, 0888, 1006, 0946 and 0623)
1875 Mixed Adrenergic Tocriset™
Selection of 5 mixed adrenoceptor ligands (Cat. Nos. 0888, 0425, 1747, 0623 and 0952)
Ligands
Cat.No.
Product Name / Activity
0998 AH 11110 hydrochloride
Subtype-selective α1B ligand
0581 3-MPPI
α1 ligand
Related Categories

Quick Order

Find multiple products by catalog number

divider line

Cardiovascular Research Product Guide

Cardiovascular Research Product Guide

Our Cardiovascular Guide highlights over 250 products for cardiovascular research. Request copy or view PDF today.

divider line

GPCR Product Listing

GPCR Product Listing

Highlights over 450 products for GPCRs. Request copy or view PDF today.

divider line

Regulation of Vascular Reactivity by GPCRs

Written by J.J. Maguire and A.P. Davenport

Cardiovascular Life Science Poster

Our Cardiovascular poster highlights the key G protein-coupled receptors involved in the regulation of vascular reactivity. Request copy today.

divider line

Antidepressants - Current and Future Targets

Written by P. Skolnich et al

Depression Life Science Poster

Our Depression poster highlights presynaptic and postsynaptic targets for the potential treatment of major depressive disorder. Request copy or view PDF today.

divider line

Bio-Techne Events

Pharmacology 2016

Pharmacology 2016

December 13 - 15, 2016

London, UK

Booth: 7