Chemokine CXC Receptors

More Information »Chemokine CXC receptors (CXCRs) predominantly recognize CXC chemokines. CXC chemokines are distinguished by having four conserved cysteines, with the first two cysteines being separated by a single amino acid. There are six chemokine CXC receptors.

Chemokine CXC Receptor Products

Agonists
Cat.No.
Product Name / Activity
5795 ATI 2341
CXCR4 allosteric agonist
4780 VUF 11207 fumarate
Potent ACKR3 (CXCR7) agonist
5668 VUF 11222
High affinity non-peptide CXCR3 agonist
Antagonists
Cat.No.
Product Name / Activity
3299 AMD 3100 octahydrochloride
Highly selective CXCR4 antagonist
4179 AMD 3465 hexahydrobromide
Potent and selective CXCR4 antagonist
4487 (±)-AMG 487
CXCR3 antagonist; inhibits cell migration and metastasis
5872 AZ 10397767
Potent CXCR2 antagonist
5130 CTCE 9908
CXCR4 antagonist; antitumor
4320 FC 131
CXCR4 antagonist
4596 IT1t dihydrochloride
Potent CXCR4 antagonist
5943 ML 339
Potent and selective hCXCR6 antagonist
4528 (±)-NBI 74330
Potent and selective CXCR3 antagonist
5660 NVP CXCR2 20
Potent and selective CXCR2 antagonist
2725 SB 225002
Potent and selective CXCR2 antagonist
2724 SB 265610
Potent CXCR2 antagonist
5671 SB 332235
Potent CXCR2 antagonist
4300 TC 14012
CXCR4 antagonist; ACKR3 (CXCR7) agonist
3951 WZ 811
Potent CXCR2 antagonist

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