Inward Rectifier Potassium (Kir) Channels
The inward-rectifier potassium channel family (also known as 2-TM channels) include the strong inward-rectifier channels (Kir2.x), the G-protein-activated inward-rectifier channels (Kir3.x) and the ATP-sensitive channels (Kir6.x), which combine with sulphonylurea receptors (SUR).
Structurally, the pore-forming subunit of Kir channels is the α-subunit. It contains a single pore domain between two membrane spanning regions. Four α-subunits combine to form a tetramer, with the pore domain of each subunit contributing to the structure of the central pore. Heteromeric channels can also be formed within subfamilies, e.g. Kir3.2 with Kir3.3.View all products for Inward Rectifier Potassium (Kir) Channels »
|Gene||Species||Gene Symbol||Gene Accession No.||Protein Accession No.|
|KIR1.1 (ROMK1) (ATP-sensitive)||Human||KCNJ1||NM_000220||P48048|
|View all KIR Channel Gene Data »|
Literature for Inward Rectifier Potassium (Kir) Channels
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