Isocitrate Dehydrogenase 1 (IDH1)

More Information »Isocitrate dehydrogenase 1 (IDH1) EC:1.1.1.42 is one of three isocitrate dehydrogenase isoforms found in humans. Mutated IDH1 catalyzes α-KG to D-2-hydroxyglutarate (D2HG) and has been linked to tumorigenesis in certain types of cancers.

Isocitrate Dehydrogenase 1 (IDH1) Products

Inhibitors
Cat.No.
Product Name / Activity
5244 TC-E 5008
Selective mutant isocitrate dehydrogenase 1 (mIDH1) inhibitor; phenotypically lethal
Other
Cat.No.
Product Name / Activity
6124 (R)-2-Hydroxyglutaric acid disodium salt
Oncometabolite produced by mutant isocitrate dehydrogenase
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