Lysine Methyltransferases

More Information »Lysine methyltransferases are enyzmes that catalyze the transfer of methyl groups from S-adenosylmethionine (SAM) to the lysine residues on histones, particularly histones H3 and H4. The dysregulation of this methylation is critical in the development of cancer.

Lysine Methyltransferase Products

Product Name / Activity
6167 A 196
Potent and selective SUV420H1/H2 inhibitor
5163 A 366
Potent and selective G9a/GLP inhibitor
3364 BIX 01294
GLP and G9a inhibitor
6282 BRD 4770
G9a inhibitor and S-adenosyl methionine mimetic; cell permeable
4504 Chaetocin
SUV39H1 inhibitor
0996 Cyproheptadine hydrochloride
SETD7/9 inhibitor; also 5HT2 antagonist
4703 3-Deazaneplanocin A hydrochloride
EZH2 histone methyltransferase inhibitor
5567 EPZ 004777
Highly potent DOT1L inhibitor
6128 GSK 343
Potent and selective SAM-competitive EZH2 inhibitor
5365 LLY 507
Potent SMYD2 inhibitor
6169 PF 06726304 acetate
Highly potent and SAM-competitive EZH2 inhibitor
4892 (R)-PFI 2 hydrochloride
Potent and selective SETD7 inhibitor
5400 (S)-PFI 2 hydrochloride
Negative control of (R)-PFI 2 hydrochloride (Cat. No. 4892)
2609 Ryuvidine
SETD8 inhibitor; also CDK4 inhibitor
4541 SGC 0946
Highly potent and selective DOT1L inhibitor; cell permeable
3861 UNC 0224
Potent G9a and GLP inhibitor
4343 UNC 0638
Selective G9a and GLP inhibitor
5132 UNC 0642
Potent and selective G9a and GLP inhibitor
4342 UNC 0646
Potent and selective G9a and GLP inhibitor
4904 UNC 1999
Potent and selective EZH2/EZH1 inhibitor
4930 UNC 2399
Biotinylated UNC 1999 (Cat.No. 4904)
4905 UNC 2400
Negative control of UNC 1999 (Cat. No. 4904)
Product Name / Activity
4707 MI 2 dihydrochloride
Menin-MLL interaction inhibitor
5307 MM 102
WDR5/MLL interaction inhibitor
5267 OICR 9429
High affinity and selective WDR5 antagonist
5323 WDR5 0103
WDR5 antagonist
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