PORCN

More Information »Porcupine (PORCN) is a membrane bound O-acyltransferase (MBOAT) that is involved in the acylation (palmitoylation) of Wnt proteins. Palmitoylation is essential for Wnt secretion and signaling, with PORCN inhibitors showing efficacy in inhibiting Wnt-driven tumorigenesis.

PORCN Products

Inhibitors
Cat.No.
Product Name / Activity
5279 IWP 12
Potent PORCN inhibitor; active in vivo
3533 IWP 2
PORCN inhibitor; inhibits Wnt processing and secretion
4992 IWP L6
Potent PORCN inhibitor
5148 Wnt-C59
Highly potent PORCN inhibitor
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