PERK

More Information »PKR-like ER kinase (PERK, EIF2AK3) is an elF2α kinase that inhibits protein translation. PERK is a type one endoplasmic reticulum (ER) membrane protein which is involved in both the integrated stress response (ISR) and unfolded protein response (UPR).

PERK Products

Inhibitors
Cat.No.
Product Name / Activity
5517 AMG PERK 44
Potent and selective PERK inhibitor; orally bioavailable
5107 GSK 2606414
Potent and selective PERK inhibitor; orally bioavailable
Other
Cat.No.
Product Name / Activity
5796 Azoramide
Unfolded protein response (UPR) modulator
5284 trans-ISRIB
Integrated stress response (ISR) inhibitor
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