More Information »Dual-specificity tyrosine phosphorylation-regulated kinases (DYRKs) are conserved serine/threonine kinases. DYRKs have been implicated in cell survival, proliferation and differentiation, and in the pathology of Down Syndrome and Alzheimer's disease.

DYRK Products

Product Name / Activity
5232 AZ 191
Potent DYRK1B inhibitor
5632 AZ Dyrk1B 33
Potent and selective Dyrk1B kinase inhibitor
5075 Harmine
Potent and selective DYRK1A inhibitor
4997 INDY
DYRK1A/B inhibitor
5700 ML 315 hydrochloride
Inhibitor of Clk and DYRK kinases
4998 ProINDY
DYRK1A/B inhibitor; prodrug of INDY (Cat. No. 4997)
5088 TC-S 7004
Potent and selective DYRK1A/B inhibitor
4336 TG 003
Potent DYRK1A/B inhibitor; also inhibitor of Clk-family kinases
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