Ryanodine Receptors

More Information »The ryanodine receptors (RyRs) are a family of Ca2+ channels that mediate the release of Ca2+ from intracellular Ca2+ storage organelles. Three RyR isoforms have been identified to date, RyR1, RyR2 and RyR3, roles of which include contraction, secretion and synaptic transmission.

Ryanodine Receptor Products

Modulators
Cat.No.
Product Name / Activity
2793 Caffeine
Mobilizes calcium from intracellular stores
3905 NAADP tetrasodium salt
Ca2+ mobilizing agent
1472 Suramin hexasodium salt
Increases RYR open probability
Inhibitors
Cat.No.
Product Name / Activity
0507 Dantrolene, sodium salt
Ca2+ release inhibitor
4564 JTV 519 fumarate
Ryanodine receptor (RyR) inhibitor
1439 Ruthenium Red
Inhibits ryanodine-sensitive Ca2+ release
1329 Ryanodine
Ca2+ release inhibitor
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