MBT Domains

More Information »Malignant Brain Tumor (MBT) domains are a family of methylated lysine-recognizing transcriptional repressors. They possess a methyl-lysine (Kme) binding pocket along with other Kme reader proteins, but MBT domains selectively recognize mono- and dimethylated lysines.

MBT Domain Products

Product Name / Activity
4666 UNC 1215
Potent inhibitor of L3MBTL3 Kme reader domain; cell permeable
4516 UNC 926 hydrochloride
L3MBTL1 domain inhibitor

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Cancer Research Product Guide

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Epigenetics Review

Written by S. Müller-Knapp & P. Brown

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Our Epigenetics review gives an overview of the development of chemical probes for epigenetic targets, and discusses their biological effects. Request copy or view PDF today.

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The epigenetics research bulletin gives an introduction into mechanisms of epigenetic regulation, and highlights key Tocris products for epigenetics targets. View PDF today.

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