Catechol O-Methyltransferase

More Information »Catechol O-Methyltransferase (COMT) (EC 2.1.1.6) catalyzes the transfer of a methyl group from S-adenosyl-L-methionine (AdoMet) to a catechol substrate, such as dopamine or levodopa, in the presence of magnesium (Mg2+) ions.

Catechol O-Methyltransferase Products

Inhibitors
Cat.No.
Product Name / Activity
4720 Entacapone
Potent COMT inhibitor; blocks α-synuclein aggregation
0483 OR-486
Catechol O-methyltransferase inhibitor
5864 Tolcapone
COMT inhibitor; also inhibits transthyretin aggregation
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