More Information »The polycystin transient receptor potential (TRPP) channels are a subfamily of TRP channels that, when mutated, can lead to polycystic kidney disease. TRPP channels are divided into two distinct groups, polycystic kidney disease 1-like and polycystic kidney disease 2-like.

TRPP Products

Product Name / Activity
0890 Amiloride hydrochloride
Na+ channel blocker; inhibits TRPP3 channel
3380 Benzamil
NCX inhibitor; inhibits TRPP3 channel activity
3378 EIPA
Inhibits TRPP3-mediated currents; also inhibits the Na+/H+ exchanger (NHE)
3379 Phenamil
Inhibits TRPP3-mediated currents; also inhibits epithelial Na+ channels

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