Glucose Transporters

Supporting information

Glucose is an essential source of energy for mammalian cells, and is also used as a substrate in protein and lipid synthesis. Given its hydrophilic nature, glucose must be transported into the cell by dedicated transporters; these are encoded by genes known collectively as the facilitative glucose transporter gene family (GLUT). There are 13 known members of the GLUT family.

Glucose transporters maintain a ready supply of glucose for the cell's metabolic activity. During growth and division, the energy demands of a cell are increased; it needs glucose to generate ATP and biomass. Cancer cells, which proliferate at a greater rate, thus require more energy than a normal cell. Aerobic glycolysis - often observed in tumor cells, and also known as the Warburg effect - relies on a high rate of glucose uptake, since the generation of ATP by this process is far less efficient than oxidative phosphorylation. Glucose transporters, in particular GLUT1, have therefore become a target of interest in cancer research, as have glycolytic inhibitors.

View all products for Glucose Transporters »
Gene Species Gene Symbol Gene Accession No. Protein Accession No.
Solute carrier family 2 (facilitated glucose transporter), member 1
Human SLC2A1 NM_006516 P11166
Mouse Slc2a1 NM_011400 P17809
Rat Slc2a1 NM_138827 P11167
Solute carrier family 2 (facilitated glucose transporter), member 2
Human SLC2A2 NM_000340 P11168
Mouse Slc2a2 NM_031197 P14246
Rat Slc2a2 NM_012879 P12336
View all Glucose Transporter Gene Data »

Literature for Glucose Transporters

Cancer Research Product Guide

A collection of over 750 products for cancer research, the guide includes research tools for the study of:

  • Cancer Metabolism
  • Epigenetics in Cancer
  • Receptor Signaling
  • Cell Cycle and DNA Damage Repair
  • Angiogenesis
  • Invasion and Metastasis
Request copy | Download PDF | View all Product Guides & Listings
Cancer Research Product Guide

Quick Order

Find multiple products by catalog number

divider line

Cancer Research Product Guide

Cancer Research Product Guide

Our Cancer Research Guide highlights over 750 products for cancer research. Request copy or view PDF today.

divider line

Twitter Updates

Follow @Tocris on Twitter

Follow us on Twitter!

Tocris is now actively tweeting. For regular updates on news, events and special offers, follow @Tocris on Twitter.