Leukotriene A4 Hydrolase

Supporting information

Leukotriene A4 hydrolase, (LTA4 hydrolase, LTA4H) is a zinc-dependent epoxide hydrolase which hydrolyzes LTA4 to form LTB4 during leukotriene biosynthesis. The enzyme is the only member of the leukotriene biosynthetic pathway which is mainly cytoplasmic.

LTA4 hydrolase is expressed in monocytes, lymphocytes, neutrophils, fibroblasts and platelets. In addition to its actions during LTB4 synthesis, LTA4 hydrolase also possesses aminopeptidase activity and is known to degrade the neutrophil chemoattractant, PGP (proline-glycine-proline). This activity has been linked to the resolution of acute, neutrophil-driven inflammation.

View all products for Leukotriene A4 Hydrolase »
Gene Species Gene Symbol Gene Accession No. Protein Accession No.
LTA4H Human LTA4H NM_000895 P09960
Mouse Lta4h NM_008517 P24527
Rat Lta4h NM_001030031 Q499P2

Literature for Leukotriene A4 Hydrolase

Immunology Product Listing

A collection of over 190 products for immunology research, the guide includes research tools for the study of:

  • Chemokine and Cytokine Signaling
  • Chemotaxis
  • Complement System
  • Immune Cell Signaling
  • Inflammation
Request copy | Download PDF | View all Product Guides & Listings
Immunology Product Listing

Quick Order

Find multiple products by catalog number

divider line

Immunology Guide

Immunology Product Listing

Our Immunology listing highlights over 190 products for immunology research. Request copy or view PDF today.

divider line

Bio-Techne Events

SENC 2017

17th National Congress of the Spanish Society of Neuroscience

September 27 - 30, 2017

Alicante, Spain