Pregnane X Receptors

More Information »Pregnane X receptors (PXRs) are nuclear receptors that regulate the expression of CYP3A genes, generating key enzymes involved in xenobiotic metabolism. PXRs also help regulate the induction of P-gp. PXRs are highly expressed in the liver, small intestine and colon.

Pregnane X Receptor Products

Agonists
Cat.No.
Product Name / Activity
4245 Meclizine dihydrochloride
Human pregnane X receptor agonist; H1 antagonist
4121 Rifampicin
Pregnane X receptor agonist; antibiotic
5359 Rifaximin
Pregnane X receptor agonist; antibiotic
2969 SR 12813
Pregnane X receptor agonist
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