Pregnane X Receptors

More Information »Pregnane X receptors (PXRs) are nuclear receptors that regulate the expression of CYP3A genes, generating key enzymes involved in xenobiotic metabolism. PXRs also help regulate the induction of P-gp. PXRs are highly expressed in the liver, small intestine and colon.

Pregnane X Receptor Products

Product Name / Activity
4245 Meclizine dihydrochloride
Human pregnane X receptor agonist; H1 antagonist
4121 Rifampicin
Pregnane X receptor agonist; antibiotic
5359 Rifaximin
Pregnane X receptor agonist; antibiotic
2969 SR 12813
Pregnane X receptor agonist
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Nuclear Receptors Product Listing

Nuclear Receptors Product Listing

Our Nuclear Receptors Listing highlights over 150 products for nuclear receptors. Request copy or view PDF today.

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RXR and RAR Scientific Review

Written by Alexander Moise

Retinoid Receptors Scientific Review

Our Retinoid Receptor review gives a summary of retinoic acid and retinoid X receptor pharmacology, and the modulation of retinoid signaling. Request copy or view PDF today.

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26th ISN-ESN Biennal Meeting

26th ISN-ESN Biennial Meeting

August 20 - 24, 2017

Paris , France

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