Antivirals are drugs that inhibit viral infection, targeting virus entry, assembly or replication. Mechanisms of antiviral action include blocking virus replication at key points, such as interfering with DNA polymerization or protease inhibition. They are used to treat viral infections such as HIV and CMV.

Antiviral Products

Product Name / Activity
6258 CC 401 dihydrochloride
Inhibitor of HCMV replication; also high affinity JNK inhibitor
6234 Entecavir
Potent and selective hepatitis B virus inhibitor
6183 Nanchangmycin
Antiviral; active against Zika, West Nile and dengue viruses
Product Name / Activity
5612 18A
HIV cell entry blocker
4148 Abacavir hemisulfate
Reverse transcriptase inhibitor; antiretroviral
5852 Acetyl Pepstatin
Aspartic protease inhibitor; inhibits HIV-1/2 proteinases
2513 Acyclovir
Antiviral agent; active against herpes simplex viruses
5736 Aphidicolin
Antiviral; inhibits DNA polymerase α, δ and ε
2151 API-2
Selective inhibitor of Akt/PKB signaling. Antitumor and antiviral
1777 Arctigenin
Potent MEK1 inhibitor; antiproliferative and antiviral agent
2457 Arcyriaflavin A
cdk4/cyclin D1 inhibitor; inhibits human cytomegalovirus
4150 Azidothymidine
Selective reverse transcriptase inhibitor; antiretroviral
2711 Bay 55-9837
VPAC2 agonist; reduces HIV-1 viral replication
5009 BMS 509744
ITK kinase inhibitor; attenuates establishment of HIV infection
2743 Caffeic acid phenethyl ester
Inhibitor of NFκB activation; antiviral agent
2483 Costunolide
Telomerase inhibitor; displays antiviral properties
1437 D609
Phosphatidyl choline-specific phospholipase C inhibitor; antitumor agent
2423 DAPTA
CCR5 antagonist; selective antiviral for R5 tropic HIV-1 strains
1770 Deguelin
Anticancer and antiviral agent; pro-apoptotic
4149 Delavirdine mesylate
Non-nucleoside reverse transcriptase inhibitor
5601 DMXAA
mSTING agonist; antiviral
4320 FC 131
CXCR4 antagonist; displays anti-HIV activity
5741 25-Hydroxycholesterol
Antiviral; also α-crystallin (cryAB) chaperone
1520 Hypericin
Photosensitive antiviral, anticancer and antidepressant agent
3700 Imiquimod
Immunomodulator; has antiviral and antitumor activity
4596 IT1t dihydrochloride
Potent CXCR4 antagonist; blocks interaction with the HIV envelope protein
2287 K-252c
PKC inhibitor; antiviral against strains of human cytomegalovirus
2307 Leukotriene B4
Lipid inflammatory mediator; antiviral towards DNA viruses and retroviruses
3756 Maraviroc
Selective CCR5 antagonist; inhibits HIV-1 cell entry
5604 MI 14
Potent and selective PI 4-kinase IIIβ inhibitor
3117 Miglustat hydrochloride
Glycosyltransferase inhibitor; broad spectrum antiviral activity
1505 Mycophenolic acid
Inosine monophosphate dehydrogenase inhibitor; antiviral and antitumor
5811 NBD 556
CD4 mimetic; blocks HIV-1 cell entry
3766 Nelfinavir mesylate
Potent HIV-1 protease inhibitor
3354 PF 429242
Competitive inhibitor of SREBP site 1 protease; antiviral
4536 Resiquimod
Toll-like receptor 7 (TLR7) agonist; antiviral
4501 Ribavirin
Antiviral guanosine analog; blocks eIF4E activity
5856 Ritonavir
HIV-1 and HIV-2 protease inhibitor
5389 Ro 48-8071 fumarate
Inhibits Ebola virus (EBOV) cell entry; OSC inhibitor
4694 Ro 5-3335
Core binding factor inhibitor; inhibits HIV-1 replication
0630 Rosmarinic acid
Anti-inflammatory, cytostatic and antiviral; GPR35 agonist
2719 RWJ 21757
Toll-like receptor 7 (TLR7) agonist; displays antitumor and antiviral activity
4418 Saquinavir mesylate
HIV protease inhibitor
1410 SDM25N hydrochloride
Inhibits dengue virus replication; also potent, selective non-peptide δ antagonist
4990 Stavudine
Nucleoside analog; antiviral
1472 Suramin hexasodium salt
P2 purinergic antagonist; anticancer and antiviral agent
3666 Tenofovir
Selectively inhibits HIV reverse transcriptase
3356 WR 1065
p53 activator; exhibits broad spectrum antiviral activity

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