M1 Receptors

More Information »M1 receptors are members of the G-protein-coupled receptor (GPCR) family which are found mostly bound to Gq proteins. They are one of five muscarinic receptors that act to control the metabotropic functions of acetylcholine (ACh) in the central nervous system (CNS).

M1 Receptor Products

Agonists
Cat.No.
Product Name / Activity
3689 Cevimeline hydrochloride
Selective M1 agonist
1384 McN-A 343
Selective M1 muscarinic agonist
3569 Xanomeline oxalate
Functionally selective M1 agonist
Antagonists
Cat.No.
Product Name / Activity
2853 Biperiden hydrochloride
Muscarinic receptor antagonist; some selectivity for M1
0469 Nitrocaramiphen hydrochloride
Muscarinic antagonist, M1 > M2
1071 Pirenzepine dihydrochloride
Selective M1 muscarinic antagonist
1122 Telenzepine dihydrochloride
Potent, selective M1 antagonist
3727 VU 0255035
Highly selective muscarinic M1 antagonist
Modulators
Cat.No.
Product Name / Activity
4295 VU 0357017 hydrochloride
Positive allosteric modulator of M1 receptors
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