TRPM

More Information »The melastatin-related receptor family (TRPM) is the largest subfamily of the transient receptor potential (TRP) superfamily of ion channels. It contains 8 known members, subdivided into 4 groups, which perform a range of functions including detection of taste and osmolarity.

TRPM Products

Agonists
Cat.No.
Product Name / Activity
5521 CIM 0216
Selective TRPM3 agonist
1531 Icilin
Activates a novel cold receptor. Cooling agent
3040 WS 12
TRPM8 agonist; cooling agent
2927 WS 3
TRPM8 agonist; cooling agent
Antagonists
Cat.No.
Product Name / Activity
5388 RQ 00203078
Potent and selective TRPM8 antagonist; orally active
5410 TC-I 2014
Potent TRPM8 antagonist
Activators
Cat.No.
Product Name / Activity
5376 Pregnenolone sulfate sodium salt
NMDA Potentiator; activates TRPM3 channels
Blockers
Cat.No.
Product Name / Activity
3989 AMTB hydrochloride
TRPM8 blocker
5324 M8 B hydrochloride
Potent and selective TRPM8 channel blocker
5143 Ononetin
TRPM3 blocker
6003 PF 05105679
Selective TRPM8 blocker
4999 9-Phenanthrol
Selective TRPM4 blocker
4632 TC-I 2000
TRPM8 blocker
Other
Cat.No.
Product Name / Activity
1268 U 73122
TRPM4 activator and TRPM3 blocker; also phospholipase C inhibitor
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