CRF1 Receptors

Supporting information

The corticotropin-releasing factor (CRF) 1 receptor is a member of the corticotropin-releasing factor family of G-protein-coupled receptors that also includes CRF2. It is abundantly expressed in the CNS with major expression in the cortex, cerebellum, hippocampus, amygdala, olfactory bulb and pituitary. In the periphery the receptors are expressed at low levels in the skin, ovary, testis and adrenal gland.

To view external sources of pharmacological information for CRF1 Receptors, please click here: IUPHAR Receptor Code and BJP Guide

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Species Gene Symbol Gene Accession No. Protein Accession No.
Human CRHR1 NM_004382 P34998
Mouse Crhr1 NM_007762 P35347
Rat Crhr1 NM_030999 P35353

Literature for CRF1 Receptors

GPCR Product Listing

A collection of over 450 products for G protein-coupled receptors, the listing includes research tools for the study of:

  • Rhodopsin-like Receptors
  • Secretin-like Receptors
  • Glutamate Receptors
  • Frizzled Receptors
  • GPCR Signaling
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GPCR Product Listing
Peptide Hormone Receptors Product Listing

A collection of over 200 products for peptide hormone receptors, the listing includes research tools for the study of:

  • Anterior Pituitary Regulation
  • Blood Pressure Regulation
  • Feeding and Appetite Regulation
  • Glucose Regulation
  • Peptide Hormone Processing
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Peptide Hormone Receptors Product Listing
Depression Life Science Poster

Written by Phil Skolnick, Piotr Popik and Ramon Trullas and updated in 2015, this poster highlights presynaptic and postsynaptic targets for the potential treatment of major depressive disorder, as well as outlining the pharmacology of currently approved antidepressant drugs. Compounds available from Tocris are listed.

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Depression Life Science Poster
Gut Hormones Life Science Poster

Written by Victoria Taylor et al, this poster summarizes the major gut hormones and neuropeptide modulators that influence digestion, appetite and energy expenditure. The intracellular targets of stimulatory and inhibitory hormones and the role of the hypothalamus in signal integration are also described. Compounds available from Tocris are listed.

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Gut Hormones Life Science Poster

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Peptide Hormone Receptors Product Listing

Peptide Hormone Receptors Product Listing

Our Peptide Hormone Receptors Listing highlights over 200 products for peptide hormone receptors. Request copy or view PDF today.

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GPCR Product Listing

GPCR Product Listing

Highlights over 450 products for GPCRs. Request copy or view PDF today.

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Gut Hormones and the Regulation of Appetite

Written by V.J. Taylor et al

Gut Hormones Life Science Poster

Our Gut Hormones and the Regulation of Appetite poster gives an overview of the neuropeptide modulators and gut hormones that influence appetite. Request copy today.

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Antidepressants - Current and Future Targets

Written by P. Skolnich et al

Depression Life Science Poster

Our Depression poster highlights presynaptic and postsynaptic targets for the potential treatment of major depressive disorder. Request copy or view PDF today.

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