Fatty Acid Amide Hydrolase

Supporting information

Fatty acid amide hydrolase, (FAAH, Oleamide hydrolase, Anandamide amidohydrolase), is an integral membrane protein that hydrolyzes bioactive amides, including anandamide, to free fatty acid and ethanolamine.

FAAH distribution is noticeably different between human and rat. In humans, FAAH is mainly present in the pancreas, brain, kidney, skeletal muscle, and placenta. In rat, FAAH is mainly detected in the liver, small intestine, brain, kidney, spleen, testis, and uterus, but is absent from skeletal muscle and heart. A second FAAH (FAAH2) was identified recently in humans but is absent from rats and mice.

View all products for Fatty Acid Amide Hydrolase »
Gene Species Gene Symbol Gene Accession No. Protein Accession No.
FAAH1 Human FAAH NM_001441 O00519
Mouse Faah NM_010173 O08914
Rat Faah NM_024132 P97612
FAAH2 Human FAAH2 NM_174912 Q6GMR7

Literature for Fatty Acid Amide Hydrolase

Pain Research Product Guide

A collection of over 250 products for pain research, the guide includes research tools for the study of:

  • Nociception
  • Ion Channels
  • G-Protein-Coupled Receptors
  • Intracellular Signaling
Request copy | Download PDF | View all Product Guides & Listings
Pain Research Product Guide
Cannabinoid Receptor Ligands Scientific Review

Two types of cannabinoid receptor have so far been identified. This review focuses particularly on ligands that are most widely used as experimental tools and denotes compounds available from Tocris.

Request copy | Download PDF | View all reviews
Cannabinoid Receptor Ligands Scientific Review
Addiction Life Science Poster

Written by Prof David Nutt, this poster summarizes the brain circuits associated with addiction and outlines the main classes of addictive drugs and neurotransmitter systems affected by them. Compounds available from Tocris for addiction research are listed.

Request copy | Download PDF | View all posters
Addiction Life Science Poster

Quick Order

Find multiple products by catalog number

divider line

Pain Research Product Guide

Pain Research Product Guide

Our Pain guide highlights over 280 products for Pain research. Request copy or view PDF today.

divider line

Cannabinoid Review

Written by Roger Pertwee

Cannabinoid Receptor Ligands Scientific Review

Our Cannabinoid review gives an overview of the pharmacological ligands used to study the cannabinoid CB1 and CB2 receptors. Request copy or view PDF today.

divider line

Mechanisms of Addiction

Addiction Life Science Poster

Written by Prof David Nutt, this poster summarizes the brain circuits and neurotransmitter systems that are affected by the main classes of addictive drugs. Request copy or view PDF today.

divider line

LinkedIn Updates

Follow Tocris on LinkedIn

Follow us on LinkedIn!

Visit our LinkedIn page for the latest Tocris news, events and updates.