PPARγ

More Information »Peroxisome proliferator-activated receptor gamma (PPARγ) is a member of the nuclear receptor family of ligand-activated transcription factors that heterodimerize with the retinoic X receptor (RXR) to regulate gene expression.

PPARγ Products

Agonists
Cat.No.
Product Name / Activity
1307 Ciglitazone
Selective PPARγ agonist
4784 Edaglitazone
Potent and selective PPARγ agonist; antidiabetic
1664 GW 1929 hydrochloride
Selective PPARγ agonist. Orally active
3831 LG 100754
RXR:PPAR agonist; sensitizes PPARγ
2150 nTZDpa
Potent, selective PPARγ partial agonist
4124 Pioglitazone hydrochloride
Selective PPARγ agonist; antidiabetic agent
2306 15-deoxy-Δ-12,14-Prostaglandin J2
Endogenous PPARγ agonist
5325 Rosiglitazone
Potent and selective PPARγ agonist; antidiabetic agent.
3690 S26948
Selective PPARγ agonist; antidiabetic agent
5139 Telmisartan
PPARγ partial agonist; AT1 antagonist
3114 Troglitazone
Selective PPARγ agonist; antidiabetic agent
Antagonists
Cat.No.
Product Name / Activity
1326 BADGE
PPARγ antagonist
4344 FH 535
PPARγ/δ antagonist; also inhibits Wnt/β-catenin signaling
1508 GW 9662
Selective PPARγ antagonist
2022 SR 202
Selective PPARγ antagonist; antidiabetic and antiobesity agent
2301 T 0070907
Highly potent and selective PPARγ antagonist
Other
Cat.No.
Product Name / Activity
1110 Genistein
PPARγ ligand. Also estrogen receptor ligand and EGFR inhibitor
4409 SR 1664
High affinity PPARγ ligand; blocks Cdk5-dependent PPARγ phosphorylation
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