OX1 Receptors

Supporting information

The OX1 receptors, also known as hypocretin receptor 1, are located primarily in the ventromedial hypothalamus, locus coeruleus, median raphe, hippocampus and taenia tecta where they are thought to regulate sleep-wakefulness and energy homeostasis. The OX1 receptor displays higher affinity for Orexin A over Orexin B. The human OX1 receptor gene has been localized to chromosome 1 (1p33).

To view external sources of pharmacological information for OX1 Receptors, please click here: IUPHAR Receptor Code and BJP Guide

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Species Gene Symbol Gene Accession No. Protein Accession No.
Human HCRTR1 NM_001525 O43613
Mouse Hcrtr1 NM_198959 P58307
Rat Hcrtr1 NM_013064 P56718

Literature for OX1 Receptors

GPCR Product Listing

A collection of over 450 products for G protein-coupled receptors, the listing includes research tools for the study of:

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  • Secretin-like Receptors
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  • Frizzled Receptors
  • GPCR Signaling
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GPCR Product Listing
Peptide Hormone Receptors Product Listing

A collection of over 200 products for peptide hormone receptors, the listing includes research tools for the study of:

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  • Blood Pressure Regulation
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  • Glucose Regulation
  • Peptide Hormone Processing
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Peptide Hormone Receptors Product Listing
Peptides Involved in Appetite Modulation Scientific Review

A synopsis of the increasing number of peptides that have been implicated in appetite regulation and energy homeostasis, outlining the putative roles of most of the known proteins and lists compounds available from Tocris.

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Peptides Involved in Appetite Modulation Scientific Review

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Peptide Hormone Receptors Product Listing

Peptide Hormone Receptors Product Listing

Our Peptide Hormone Receptors Listing highlights over 200 products for peptide hormone receptors. Request copy or view PDF today.

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GPCR Product Listing

GPCR Product Listing

Highlights over 450 products for GPCRs. Request copy or view PDF today.

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Appetite Modulation

Written by S. Tucci et al

Peptides Involved in Appetite Modulation Scientific Review

Our Peptides Involved in Appetite Modulation review gives an overview of the peptides implicated in appetite regulation and energy homeostasis. View PDF today.

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