MEK

More Information »MEK, also known as Mitogen-activated protein kinase kinase and MAP2K, is a kinase enzyme that phosphorylates mitogen activated protein kinases (MAPKs), ERK, p38 and JNK. Seven MEK subtypes have been identified, all mediate cellular responses to different growth signals.

MEK Products

Inhibitors
Cat.No.
Product Name / Activity
1777 Arctigenin
Potent MEK1 inhibitor. Also inhibits IκBα phosphorylation
4842 BIX 02189
Selective MEK5 and ERK5 inhibitor
1532 10Z-Hymenialdisine
Pan kinase inhibitor; potently inhibits MEK1
4192 PD 0325901
Potent inhibitor of MEK1/2
4237 PD 184352
Selective MEK inhibitor
2605 PD 198306
Selective inhibitor of MEK1/2
4824 PD 334581
MEK1 inhibitor
1213 PD 98059
MEK inhibitor
1969 SL 327
Selective inhibitor of MEK1 and MEK2; brain penetrant
1868 U0124
Inactive analog of U0126 (Cat. No. 1144)
1144 U0126
Potent, selective inhibitor of MEK1 and 2
Ligand Sets
Cat.No.
Product Name / Activity
2243 MEK Inhibitor Tocriset™
Selection of 3 MEK inhibitors (Cat. Nos. 1213, 1969 and 1144)
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