5-HT2C Receptors

More Information »Serotonin 5-HT2C receptors, previously known as 5-HT1C receptors, are located primarily in the choroid plexus, cortex, limbic system and basal ganglia. 5-HT2C receptors play a role in CSF volume regulation, thermoregulation, penile erection and anxiety.

5-HT2C Receptor Products

Agonists
Cat.No.
Product Name / Activity
3041 CP 809101 hydrochloride
Potent and selective 5-HT2C agonist
0875 m-CPP hydrochloride
5-HT2B/2C receptor agonist
2643 DOI hydrochloride
Mixed 5-HT2A/2C agonist
1860 Eltoprazine hydrochloride
5-HT2C receptor partial agonist
3017 1-Methylpsilocin
Potent and selective 5-HT2C agonist
0941 MK 212 hydrochloride
5-HT2C agonist
3585 Org 12962 hydrochloride
Selective 5-HT2C agonist
2201 PNU 22394 hydrochloride
5-HT2C agonist and 5-HT2A/2B partial agonist
1854 Ro 60-0175 fumarate
Potent, selective 5-HT2C agonist
0925 SCH 23390 hydrochloride
5-HT2C agonist; also potent dopamine D1-like antagonist, 5-HT1C agonist and Kir3 channel blocker
1801 WAY 161503 hydrochloride
Potent, selective 5-HT2C agonist
2173 WAY 629 hydrochloride
Selective 5-HT2C agonist
Antagonists
Cat.No.
Product Name / Activity
0444 Clozapine
5-HT2A/2C antagonist. Also dopamine antagonist
4936 Clozapine N-oxide
Clozapine (Cat. No. 0444) metabolite
1007 N-Desmethylclozapine
5-HT2C antagonist
1644 Mesulergine hydrochloride
5-HT2A and 5-HT2C antagonist. Also dopamine receptor partial agonist
1050 RS 102221 hydrochloride
Selective 5-HT2C antagonist
4508 S 32212 hydrochloride
5-HT2C inverse agonist; α2 antagonist
1371 SB 200646 hydrochloride
5-HT2C/2B antagonist
1661 SB 206553 hydrochloride
Potent, selective 5-HT2C/5-HT2B antagonist. Orally active
1374 SB 215505
5-HT2B/2C antagonist
1379 SB 221284
Potent, selective 5-HT2C/2B antagonist
1375 SB 228357
5-HT2C/2B antagonist/inverse agonist
2901 SB 242084
Selective 5-HT2C antagonist; brain penetrant
3527 SB 243213 dihydrochloride
Selective 5-HT2C inverse agonist
1255 SDZ SER 082 fumarate
Selective 5-HT2B/2C antagonist
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