5-HT2B Receptors

More Information »Serotonin 5-HT2B receptors, previously known as 5-HT2F receptors, are located primarily in the stomach fundus, uterus, vascular endothelial and vascular and GI smooth muscle, with limited distribution in the brain. 5-HT2B overexpression leads to ventricular hypertrophy.

5-HT2B Receptor Products

Agonists
Cat.No.
Product Name / Activity
1059 BW 723C86 hydrochloride
5-HT2B agonist
0875 m-CPP hydrochloride
5-HT2B/2C receptor agonist
0557 α-Methyl-5-hydroxytryptamine maleate
5-HT2B agonist
Antagonists
Cat.No.
Product Name / Activity
3346 ATC 0175 hydrochloride
MCH1 antagonist; also 5-HT2B antagonist and 5-HT1A partial agonist
4081 LY 266097 hydrochloride
Selective 5-HT2B receptor antagonist
3077 LY 272015 hydrochloride
High affinity 5-HT2B antagonist; orally active
2993 RS 127445 hydrochloride
Selective, high affinity 5-HT2B antagonist
1371 SB 200646 hydrochloride
5-HT2C/2B antagonist
1372 SB 204741
Potent, selective 5-HT2B antagonist
1661 SB 206553 hydrochloride
Potent, selective 5-HT2C/5-HT2B antagonist. Orally active
1374 SB 215505
5-HT2B/2C antagonist
1379 SB 221284
Potent, selective 5-HT2C/2B antagonist
1375 SB 228357
5-HT2C/2B antagonist/inverse agonist
1255 SDZ SER 082 fumarate
Selective 5-HT2B/2C antagonist
Related Categories

Quick Order

Find multiple products by catalog number

divider line

GPCR Product Listing

GPCR Product Listing

Highlights over 450 products for GPCRs. Request copy or view PDF today.

divider line

5-HT Review

Written by N. Barnes & J. Neumaler

5-HT Receptors Scientific Review

Our 5-HT review summarizes the serotonin receptor subtypes and highlights their importance in mediating various physiological & pharmacological processes. Request copy or view PDF today.

divider line

Antidepressants - Current and Future Targets

Written by P. Skolnich et al

Depression Life Science Poster

Our Depression poster highlights presynaptic and postsynaptic targets for the potential treatment of major depressive disorder. Request copy or view PDF today.

divider line

LinkedIn Updates

Follow Tocris on LinkedIn

Follow us on LinkedIn!

Visit our LinkedIn page for the latest Tocris news, events and updates.