Parathyroid Hormone Receptors

Supporting information

Parathyroid hormone (PTH) receptors are a group of Gs-protein-coupled receptors, currently divided into two subtypes: PTH1 and PTH2. Each subtype has a distinct distribution and mediates different biological actions. PTH1 is ubiquitously expressed, but is found at particularly high levels in skeletal muscle and the kidneys.

PTH1 is involved in calcium and phosphate homeostasis and has a role in chondrocyte regulation. PTH2 expression is limited to the brain and testes. Its actions are proposed to include nociception and regulation of pituitary hormone secretion. The human genes encoding the PTH1 and PTH2 receptors are located on chromosomes 3p22-21.1 and 2q33 respectively.

To view external sources of pharmacological information for Parathyroid Hormone Receptors, please click here: IUPHAR Receptor Code and BJP Guide

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Gene Species Gene Symbol Gene Accession No. Protein Accession No.
PTH1 Human PTH1R NM_000316 Q03431
Mouse Pth1r NM_001083936 P41593
Rat Pth1r NM_011199 P41593
PTH2 Human PTH2R NM_005048 P49190
Mouse Pth2r NM_139270 Q91V95
Rat Pthr2 NM_031089 P70555

Literature for Parathyroid Hormone Receptors

GPCR Product Listing

A collection of over 450 products for G protein-coupled receptors, the listing includes research tools for the study of:

  • Rhodopsin-like Receptors
  • Secretin-like Receptors
  • Glutamate Receptors
  • Frizzled Receptors
  • GPCR Signaling
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Peptide Hormone Receptors Product Listing

A collection of over 200 products for peptide hormone receptors, the listing includes research tools for the study of:

  • Anterior Pituitary Regulation
  • Blood Pressure Regulation
  • Feeding and Appetite Regulation
  • Glucose Regulation
  • Peptide Hormone Processing
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Peptide Hormone Receptors Product Listing

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Peptide Hormone Receptors Product Listing

Peptide Hormone Receptors Product Listing

Our Peptide Hormone Receptors Listing highlights over 200 products for peptide hormone receptors. Request copy or view PDF today.

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GPCR Product Listing

GPCR Product Listing

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